To reveal metabolomic changes caused by a biological event in quantitative metabolomics,
it is critical to use an analytical tool that can perform accurate and precise quantification to …

There is growing awareness of the importance of the gut microbiome in health and disease,
and recognition that the microbe to host metabolic signalling is crucial to understanding the …

The type and use of quality control (QC) samples is a 'hot topic'in metabolomics. QCs are not
novel in analytical chemistry; however since the evolution of using QCs to control the quality …

Diabetes mellitus is the most prevalent endocrine disease in the world and is likely to be the
major epidemic in human history. In current years, many modern anti-diabetic medicines …

The incidence and rate of recurrence of bladder cancer is high, particularly in developed
countries, however current methods for diagnosis are limited to detecting high-grade …

The tear film overlying the epithelial cells of the eye's surface is vital to visual function, and
its composition is reflective of ocular surface health. The ultrasmall volume of tears poses …

Metabolic fingerprinting of biological tissues has become an important area of research,
particularly in the biomarker discovery field. Methods have inherent analytical variation, and …

Systems biology has significantly increased in recent years. Its method and design resemble
those of traditional Chinese medicine (TCM), which is a unique medical system that assisted …

Through an HPLC-Q-TOF-MS-driven nontargeted metabolomics approach, we aimed to
discriminate changes in the urinary metabolome of subjects with metabolic syndrome …

Studying the effects of drugs on the metabolome constitutes a huge part of the metabolomics
discipline. Whether the approach is associated with drug discovery (altered pathways due to …