The role of IL-6 and IL-6 blockade in COVID-19

N Potere, A Batticciotto, A Vecchié… - Expert review of …, 2021 - Taylor & Francis
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a
dysregulated hyperinflammatory response. Areas covered Authors review evidence on IL-6 …

Immunopathological similarities between COVID-19 and influenza: Investigating the consequences of Co-infection

H Khorramdelazad, MH Kazemi, A Najafi… - Microbial …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been a global public health emergency since …

SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

AC Ferreira, VC Soares… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …

Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table

M Ranjbar, A Rahimi, Z Baghernejadan… - International …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

Effect of IL‐6, IL‐8/CXCL8, IP‐10/CXCL 10 levels on the severity in COVID 19 infection

F Kesmez Can, Z Özkurt, N Öztürk… - International Journal of …, 2021 - Wiley Online Library
Background COVID 19 was first observed in December 2019 and has affected the world
entire. Effective laboratory markers and prognostic indicators are needed to predict the …

Reduced expression of autophagy markers and expansion of myeloid-derived suppressor cells correlate with poor T cell response in severe COVID-19 patients

S Tomić, J Đokić, D Stevanović, N Ilić… - Frontiers in …, 2021 - frontiersin.org
Widespread coronavirus disease (COVID)-19 is causing pneumonia, respiratory and
multiorgan failure in susceptible individuals. Dysregulated immune response marks severe …

Gut microbiota dysbiosis correlates with abnormal immune response in moderate COVID-19 patients with fever

Y Zhou, X Shi, W Fu, F Xiang, X He… - Journal of …, 2021 - Taylor & Francis
Background Most COVID-19 patients are moderate, and fever is the most common clinical
manifestation and associated with poorer prognosis. Gut microbiota may also play important …

Interleukin‑6 signalling as a valuable cornerstone for molecular medicine

M Trovato, S Sciacchitano… - International …, 2021 - spandidos-publications.com
The biological abilities of interleukin‑6 (IL‑6) have been under investigation for nearly 40
years. IL‑6 works through an interaction with the complex peptide IL‑6 receptor (IL‑6R). IL‑6 …

Age-dependent immune responses in COVID-19-mediated liver injury: focus on cytokines

N Aghamohamadi, F Shahba… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is potentially pathogenic
and causes severe symptoms; in addition to respiratory syndromes, patients might …

[HTML][HTML] Effect of IL‐6, IL‐8/CXCL8, IP‐10/CXCL 10 levels on the severity in COVID 19 infection

FK Can, Z Özkurt, N Öztürk, S Sezen - International Journal of …, 2021 - ncbi.nlm.nih.gov
Background COVID 19 was first observed in December 2019 and has affected the world
entire. Effective laboratory markers and prognostic indicators are needed to predict the …