Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …

Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …

Objectives: Radiotherapy has played a limited role in the treatment of non-small cell lung
cancer (NSCLC) due to the risk of tumour radioresistance. We previously established the …

Background Glioblastoma (GBM) is the most lethal brain tumor characterized by high
morbidity and limited treatment options. Tumor malignancy is usually associated with the …

Glioma is the most pervasive intracranial tumor in the central nervous system (CNS), with
glioblastoma (GBM) being the most malignant type having a highly heterogeneous cancer …

Radiation resistance is the leading cause of radiotherapy failure in patients with cancer.
Enhanced DNA damage repair is the main reason for cancer cells to develop resistance to …

Abstract mRNA export, translation, splicing, cleavage or capping determine mRNA stability,
which represents one of the primary aspects regulating gene expression and function. RNA …

Glioblastoma multiforme (GBM) requires radiotherapy (RT) as a part of definitive
management strategy. RT is highly effective, destroying cancer cells that may exist around …

Abstract Introduction Glioma stem cells (GSCs) play an important role in glioma recurrence
and chemo‐radiotherapy (CRT) resistance. Currently, there is a lack of efficient treatment …

Neural stem cells (NSCs) were described for the first time more than two decades ago for
their ability to differentiate into all neural cell lineages. The isolation of NSCs from adults and …