The mitochondrial respiratory chain (MRC) is a key energy transducer in eukaryotic cells.
Four respiratory chain complexes cooperate in the transfer of electrons derived from various …

Having direct access to brain vasculature, astrocytes can take up available blood nutrients
and metabolize them to fulfil their own energy needs and deliver metabolic intermediates to …

The mammalian respiratory chain complexes I, III 2, and IV (CI, CIII 2, and CIV) are critical for
cellular bioenergetics and form a stable assembly, the respirasome (CI-CIII 2-CIV), that is …

Cancer stem cells (CSCs) have high tumorigenicity, high metastasis and high resistance to
treatment. They are the key factors for the growth, metastasis and drug resistance of …

Supercomplexes of the respiratory chain are established constituents of the oxidative
phosphorylation system, but their role in mammalian metabolism has been hotly debated …

Mammalian mitochondrial respiratory chain (MRC) complexes are able to associate into
quaternary structures named supercomplexes (SCs), which normally coexist with non-bound …

Anoxia halts oxidative phosphorylation (OXPHOS) causing an accumulation of reduced
compounds in the mitochondrial matrix which impedes dehydrogenases. By simultaneously …

The current view of the mitochondrial respiratory chain complexes I, III and IV foresees the
occurrence of their assembly in supercomplexes, providing additional functional properties …

In the present study, cryo‐electron tomography was used to investigate the localization of 2‐
oxoacid dehydrogenase complexes (OADCs) in cardiac mitochondria and mitochondrial …

Simple Summary Rett syndrome (RTT) is a genetic disorder caused by mutations in the X-
chromosome. These mutations distort the function of a protein (methyl-CpG-binding protein …