Animal models of epilepsy are of great importance in epileptology. They are used to study
the mechanisms of epileptogenesis, and search for new genes and regulatory pathways …

The inferior colliculus (IC) is a critical computational hub in the central auditory pathway.
From its position in the midbrain, the IC receives nearly all the ascending output from the …

Neuropeptides play key roles in shaping the organization and function of neuronal circuits.
In the inferior colliculus (IC), which is in the auditory midbrain, Neuropeptide Y (NPY) is …

Audiogenic epilepsy (AE), inherent to several rodent strains is widely studied as a model of
generalized convulsive epilepsy. The molecular mechanisms that determine the …

Despite evidence that supports cannabidiol (CBD) as an anticonvulsant agent, there
remains controversy over the antiseizure efficacy, possible adverse effects, and synergistic …

Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven
neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy …

Neuroinflammation plays an important role in epileptogenesis, however, most studies are
performed using pharmacological models of epilepsy, while there are only few data …

Rodent models of audiogenic seizures, in which seizures are precipitated by an abnormal
response of the brain to auditory stimuli, are crucial to investigate the neural bases …

The endocannabinoid system modulates epileptic seizures by regulating neuronal
excitability. It has become clear that agonist activation of central type I cannabinoid receptors …

Introduction The endocannabinoid (eCB) system is named after the discovery that
endogenous cannabinoids bind to the same receptors as the phytochemical compounds …