HIV and tuberculosis: a deadly human syndemic

CK Kwan, JD Ernst - Clinical microbiology reviews, 2011 - Am Soc Microbiol
SUMMARY A syndemic is defined as the convergence of two or more diseases that act
synergistically to magnify the burden of disease. The intersection and syndemic interaction …

Immune activation and inflammation in HIV‐1 infection: causes and consequences

V Appay, D Sauce - The Journal of Pathology: A Journal of the …, 2008 - Wiley Online Library
Thorough research on HIV is progressively enabling us to understand the intricate
mechanisms that link HIV‐1 infection to the onset of immunodeficiency. The infection and …

T Lymphocyte-Directed Gene Therapy for ADA SCID: Initial Trial Results After 4 Years

RM Blaese, KW Culver, AD Miller, CS Carter, T Fleisher… - Science, 1995 - science.org
In 1990, a clinical trial was started using retroviral-mediated transfer of the adenosine
deaminase (ADA) gene into the T cells of two children with severe combined …

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or …

JV Giorgi, LE Hultin, JA McKeating… - The Journal of …, 1999 - academic.oup.com
To define predictors of survival time in late human immunodeficiency virus type 1 (HIV-1)
disease, long-and short-duration survivors were studied after their CD4+ T cells fell to⩽ …

A TH1→ TH2 switch is a critical step in the etiology of HIV infection

M Clerici, GM Shearer - Immunology today, 1993 - cell.com
This viewpoint proposes that an imbalance in the Tul-type and TH2-type responses
contributes to the immune dysregulation associated wiib HIV infection, and that resistance to …

Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases

DR Lucey, M Clerici, GM Shearer - Clinical microbiology reviews, 1996 - Am Soc Microbiol
In the mid-1980s, Mosmann, Coffman, and their colleagues discovered that murine CD4+
helper T-cell clones could be distinguished by the cytokines they synthesized. The isolation …

Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy

M Marzi, A Vigano, D Trabattoni… - Clinical & …, 1996 - Wiley Online Library
Antigen‐and mitogen‐stimulated cytokine production by peripheral blood mononuclear cells
(PBMC) of 50 pregnant women and 31 age‐and sex‐matched non‐pregnant controls were …

Matrix-Mediated Synthesis of Nanocrystalline γ-Fe2O3: A New Optically Transparent Magnetic Material

RF Ziolo, EP Giannelis, BA Weinstein, MP O'Horo… - Science, 1992 - science.org
A new magnetic material with appreciable optical transmission in the visible region at room
temperature has been isolated as a γ-Fe2O3/polymer nanocomposite. The synthesis is …

[图书][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Cellular immune responses to HIV

AJ McMichael, SL Rowland-Jones - Nature, 2001 - nature.com
The cellular immune response to the human immunodeficiency virus, mediated by T
lymphocytes, seems strong but fails to control the infection completely. In most virus …