[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer

D Müller, B Győrffy - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

Role of DNA methylation in the resistance to therapy in solid tumors

S Romero-Garcia, H Prado-Garcia… - Frontiers in …, 2020 - frontiersin.org
Despite the recent advances in chemotherapeutic treatments against cancer, some types of
highly aggressive and invasive cancer develop drug resistance against conventional …

Multi-omics approaches in colorectal cancer screening and diagnosis, recent updates and future perspectives

I Ullah, L Yang, FT Yin, Y Sun, XH Li, J Li, XJ Wang - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …

Immunomodulatory properties of human breast milk: microRNA contents and potential epigenetic effects

MMM Hatmal, MAI Al-Hatamleh, AN Olaimat, W Alshaer… - Biomedicines, 2022 - mdpi.com
Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

Prognostic model development for classification of colorectal adenocarcinoma by using machine learning model based on feature selection technique boruta

NS Maurya, S Kushwah, S Kushwaha, A Chawade… - Scientific reports, 2023 - nature.com
Colorectal cancer (CRC) is the third most prevalent cancer type and accounts for nearly one
million deaths worldwide. The CRC mRNA gene expression datasets from TCGA and GEO …

DNA methylation and hydroxymethylation in cervical cancer: diagnosis, prognosis and treatment

H Zhu, H Zhu, M Tian, D Wang, J He, T Xu - Frontiers in Genetics, 2020 - frontiersin.org
Recent discoveries have led to the development of novel ideas and techniques that have
helped elucidate the correlation between epigenetics and tumor biology. Nowadays, the …

Methylomics and cancer: the current state of methylation profiling and marker development for clinical care

C Liu, H Tang, N Hu, T Li - Cancer Cell International, 2023 - Springer
Epigenetic modifications have long been recognized as an essential level in transcriptional
regulation linking behavior and environmental conditions or stimuli with biological …

Versatile electroanalytical bioplatforms for simultaneous determination of cancer-related DNA 5-methyl-and 5-hydroxymethyl-cytosines at global and gene-specific …

E Povedano, VRV Montiel, A Valverde… - ACS …, 2018 - ACS Publications
This paper reports the preparation of versatile electrochemical biosensing platforms for the
simple, rapid, and PCR-independent detection of the most frequent DNA methylation marks …

[HTML][HTML] The mRNA expression signature and prognostic analysis of multiple fatty acid metabolic enzymes in clear cell renal cell carcinoma

Z Zhao, Y Liu, Q Liu, F Wu, X Liu, H Qu, Y Yuan… - Journal of …, 2019 - ncbi.nlm.nih.gov
Renal cell carcinoma (RCC) is a metabolic disease, and accumulating evidences indicate
significant alterations in the cellular metabolism, especial aerobic glycolysis and glutamine …

HADHB, a fatty acid beta-oxidation enzyme, is a potential prognostic predictor in malignant lymphoma

Y Sekine, K Yamamoto, M Kurata, A Honda, I Onishi… - Pathology, 2022 - Elsevier
In haematological malignancies, such as malignant lymphoma, reprogramming of fatty acid
metabolism favours tumour cell survival and drug resistance. Hydroxyacyl-CoA …