Obstructive sleep apnea (OSA) is characterized by recurrent complete and partial upper
airway obstructive events, resulting in intermittent hypoxemia, autonomic fluctuation, and …

Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA
has well established cardiovascular and neurocognitive sequelae, although the optimal …

Rationale: Data from population-based cohorts suggest that symptom subtypes and
obstructive sleep apnea (OSA)–specific hypoxic burden (HB) could help to better identify …

Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …

Rationale: Recent studies suggest that obstructive sleep apnea (OSA) severity can vary
markedly from night to night, which may have important implications for diagnosis and …

Sleep disordered breathing causes repetitive episodes of nocturnal hypoxemia, sympathetic
nervous activation, and cortical arousal, often associated with excessive daytime sleepiness …

Background Increased mortality has been reported in people with insomnia and in those
with obstructive sleep apnoea (OSA). However, these conditions commonly co-occur and …

Rationale: Randomized controlled trials have been unable to detect a cardiovascular benefit
of continuous positive airway pressure in unselected patients with obstructive sleep apnea …

Rationale: There is currently no effective pharmacological treatment for obstructive sleep
apnea (OSA). Recent investigations indicate that drugs with noradrenergic and …

Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …