The fetal origins of memory: the role of dietary choline in optimal brain development

SH Zeisel - The Journal of pediatrics, 2006 - Elsevier
Fetal nutrition sets the stage for organ function in later life. In this review we discuss the fetal
and neonatal origins of brain function. Numerous research observations point to the …

[HTML][HTML] Oocyte cryopreservation

JK Jain, RJ Paulson - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: To review historical and contemporary advances in oocyte-cryopreservation
techniques and outcomes. DESIGN: Publications related to oocyte cryopreservation were …

Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats

JD Thomas, NM Idrus, BR Monk… - Birth Defects Research …, 2010 - Wiley Online Library
BACKGROUND: Prenatal alcohol exposure can alter physical and behavioral development,
leading to a range of fetal alcohol spectrum disorders. Despite warning labels, pregnant …

Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats

JD Thomas, EJ Abou, HD Dominguez - Neurotoxicology and teratology, 2009 - Elsevier
Prenatal alcohol exposure can lead to a range of physical, neurological, and behavioral
alterations referred to as fetal alcohol spectrum disorders (FASD). Variability in outcome …

Choline supplementation and DNA methylation in the hippocampus and prefrontal cortex of rats exposed to alcohol during development

NKH Otero, JD Thomas, CA Saski… - Alcoholism: Clinical …, 2012 - Wiley Online Library
Background Some of the most frequent deficits seen in children with fetal alcohol spectrum
disorders (FASD) and in animal models of FASD are spatial memory impairments and …

An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring

JC McCann, M Hudes, BN Ames - Neuroscience & Biobehavioral Reviews, 2006 - Elsevier
This review is part of a series intended for non-specialists that will provide an overview of
evidence for causal relationships between micronutrient deficiencies and brain function …

Maternal choline supplementation: a nutritional approach for improving offspring health?

X Jiang, AA West, MA Caudill - Trends in Endocrinology & Metabolism, 2014 - cell.com
The modulatory role of choline on the fetal epigenome and the impact of in utero choline
supply on fetal programming and health are of great interest. Studies in animals and/or …

Perinatal choline supplementation attenuates behavioral alterations associated with neonatal alcohol exposure in rats

JD Thomas, M Garrison, TM O'Neill - Neurotoxicology and teratology, 2004 - Elsevier
Children exposed to alcohol prenatally suffer from a variety of behavioral alterations,
including hyperactivity and learning deficits. Given that women continue to drink alcohol …

Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome.

J Moon, M Chen, SU Gandhy… - Behavioral …, 2010 - psycnet.apa.org
In addition to mental retardation, individuals with Down syndrome (DS) also develop the
neuropathological changes typical of Alzheimer's disease (AD) and the majority of these …

Developmental origins of the age-related decline in cortical cholinergic function and associated cognitive abilities

M Sarter, JP Bruno - Neurobiology of aging, 2004 - Elsevier
Ontogenetic abnormalities in the regulation of the cortical cholinergic input system are
hypothesized to mediate early-life cognitive limitations (ECL) that later escalate, based on …