Thrombospondin-1, CD47, and SIRPα display cell-specific molecular signatures in human islets and pancreata

N Erdem, KT Chen, M Qi, Y Zhao… - American Journal …, 2023 - journals.physiology.org
Thrombospondin-1 (TSP1) is a secreted protein minimally expressed in health but increased
in disease and age. TSP1 binds to the cell membrane receptor CD47, which itself engages …

Does hand stiffness reflect internal organ fibrosis in diabetes mellitus?

S Phatak, JL Ingram, P Goel, S Rath… - Frontiers in clinical …, 2023 - frontiersin.org
Fibrosis leads to irreversible stiffening of tissue and loss of function, and is a common
pathway leading to morbidity and mortality in chronic disease. Diabetes mellitus (both type 1 …

Biomarker Candidates for Diabetic Neuropathy among Type 2 Diabetes Mellitus Patients

M Alrawaili - 2023 - platform.almanhal.com
Background: Diabetic peripheral neuropathy (DPN) can lead to functional disabilities in type
2 diabetes mellitus (T2DM) patients. Biomarker candidates were identified based on …