Experimental diabetes induced by alloxan and streptozotocin: The current state of the art

M Radenković, M Stojanović, M Prostran - Journal of pharmacological and …, 2016 - Elsevier
Diabetes mellitus is a chronic metabolic disorder with a high prevalence worldwide. Animal
models of diabetes represent an important tool in diabetes investigation that helps us to …

A review of medicinal plants with renoprotective activity in diabetic nephropathy animal models

IMWA Putra, N Fakhrudin, A Nurrochmad, S Wahyuono - Life, 2023 - mdpi.com
Diabetic nephropathy (DN), also recognized as diabetic kidney disease, is a kidney
malfunction caused by diabetes mellitus. A possible contributing factor to the onset of DN is …

[PDF][PDF] Alloxan induced diabetes: mechanisms and effects

A Rohilla, S Ali - … journal of research in pharmaceutical and …, 2012 - researchgate.net
Diabetes mellitus is a metabolic disorder constituting a major health concern today whose
prevalence has continuously increased worldwide over the past few decades. Moreover, it …

Antidiabetic activity of zinc oxide and silver nanoparticles on streptozotocin-induced diabetic rats

A Alkaladi, AM Abdelazim, M Afifi - International journal of molecular …, 2014 - mdpi.com
The use of nanoparticles in medicine is an attractive proposition. In the present study, zinc
oxide and silver nanoparticles were evaluated for their antidiabetic activity. Fifty male albino …

Hybrid of 1-deoxynojirimycin and polysaccharide from mulberry leaves treat diabetes mellitus by activating PDX-1/insulin-1 signaling pathway and regulating the …

YG Li, DF Ji, S Zhong, ZQ Lv, TB Lin, S Chen… - Journal of …, 2011 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: 1-Deoxynojirimycin (DNJ) discovered from
mulberry trees has been reported to be a potent inhibitor of intestinal α-glycosidases …

1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice

YG Li, DF Ji, S Zhong, TB Lin, ZQ Lv, GY Hu, X Wang - Scientific reports, 2013 - nature.com
We investigated the role of 1-deoxynojirimycin (DNJ) on glucose absorption and metabolism
in normal and diabetic mice. Oral and intravenous glucose tolerance tests and labeled 13C6 …

Antidiabetic and antihyperlipidemic activities of Forsythia suspensa (Thunb.) Vahl (fruit) in streptozotocin-induced diabetes mice

Y Zhang, F Feng, T Chen, Z Li, QW Shen - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance The fruit of Forsythia suspense (Thunb.) Vahl, a well-
known Chinese Materia Medica, has been traditionally used in traditional Chinese medicine …

Isolation and characterization of anti-diabetic component (bioactivity—guided fractionation) from Ocimum sanctum L.(Lamiaceae) aerial part

R Patil, R Patil, B Ahirwar, D Ahirwar - Asian Pacific journal of tropical …, 2011 - Elsevier
Objective To isolate and characterize antidiabetic component (bioactivity-guided
fractionation) from hydro alcoholic extract of Ocimum sanctum (O. sanctum) aerial part …

Momordica charantia silver nanoparticles modulate SOCS/JAK/STAT and P13K/Akt/PTEN signalling pathways in the kidney of streptozotocin-induced diabetic rats

OO Elekofehinti, VO Oyedokun, O Iwaloye… - Journal of Diabetes & …, 2021 - Springer
Abstracts Objectives Diabetes nephropathy (DN) is one of the complications of diabetes
mellitus (DM) marked by gradual progressive loss of renal function. SOCS/JAK/STAT and …

[HTML][HTML] Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and …

Y Zhang, M Wang, H Dong… - … journal of molecular …, 2018 - spandidos-publications.com
The development of diabetes mellitus (DM) is accompanied by hyperglycemia-induced
oxidative stress. Hyperoside is a major bioactive component in Zanthoxylum bungeanum …