Context International variations in the rates of kidney cancer (KC) are considerable. An
understanding of the risk factors for KC development is necessary to generate opportunities …

Multiple hereditary syndromes predispose to kidney cancer, including Von Hippel-Lindau
syndrome, BAP1-Tumor Predisposition Syndrome, Hereditary Papillary Renal Cell …

The mammalian retina harbors over 100 different cell types. To understand how retinal
circuits work, it is essential to systematically access each type. A widely used approach for …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest
cancers, and immunotherapy could be one of the safest options to control PDAC. Although …

Increased genetic risk for melanoma can occur in the context of germline pathogenic
variants in high-penetrance genes, such as CDKN2A and CDK4, risk variants in low-to …

Objective: Small ubiquitin-related modifiers (SUMOs) are a group of post-translational
modification proteins extensively expressed in eukaryotes. Abnormal SUMOylation can lead …

Adoptif hücre tedavileri (ACT) son yıllarda malign melanomlu hastalar için mevcut en iyi
immünoterapi seçeneklerinden biridir. Tümörün baskılayıcı mikroçevresinden dolayı anti …

Napromienianie wiązką protonów jest wykorzystywane do leczenia zmian nowotworowych
ze względu na swoje właściwości fizyczne, pozwalające na precyzyjne dostarczenie …

Cutaneous melanoma (CM) is a potentially lethal form of skin cancer and its most important
histopathologic factor for staging is Breslow thickness (BT). Its correct determination is …