The TOPAS tool for particle simulation, a Monte Carlo simulation tool for physics, biology and clinical research

B Faddegon, J Ramos-Méndez, J Schuemann… - Physica Medica, 2020 - Elsevier
Purpose This paper covers recent developments and applications of the TOPAS TOol for
PArticle Simulation and presents the approaches used to disseminate TOPAS. Materials and …

The 20th Gray lecture 2019: Health and heavy ions

EA Blakely - The British journal of radiology, 2020 - academic.oup.com
Objective Particle radiobiology has contributed new understanding of radiation safety and
underlying mechanisms of action to radiation oncology for the treatment of cancer, and to …

A high-granularity digital tracking calorimeter optimized for proton CT

J Alme, GG Barnaföldi, R Barthel, V Borshchov… - Frontiers in …, 2020 - frontiersin.org
A typical proton CT (pCT) detector comprises a tracking system, used to measure the proton
position before and after the imaged object, and an energy/range detector to measure the …

[HTML][HTML] The role of Monte Carlo simulation in understanding the performance of proton computed tomography

G Dedes, J Dickmann, V Giacometti, S Rit… - … für Medizinische Physik, 2022 - Elsevier
Proton computed tomography (pCT) is a promising tomographic imaging modality allowing
direct reconstruction of proton relative stopping power (RSP) required for proton therapy …

Experimental comparison of photon versus particle computed tomography to predict tissue relative stopping powers

E Bär, L Volz, CA Collins‐Fekete, S Brons… - Medical …, 2022 - Wiley Online Library
Purpose: Measurements comparing relative stopping power (RSP) accuracy of state‐of‐the‐
art systems representing single‐energy and dual‐energy computed tomography …

The accuracy of helium ion CT based particle therapy range prediction: an experimental study comparing different particle and x-ray CT modalities

L Volz, CA Collins-Fekete, E Bär, S Brons… - Physics in Medicine …, 2021 - iopscience.iop.org
This work provides a quantitative assessment of helium ion CT (HeCT) for particle therapy
treatment planning. For the first time, HeCT based range prediction accuracy in a …

Optimization and performance study of a proton CT system for pre-clinical small animal imaging

S Meyer, J Bortfeldt, P Lämmer… - Physics in Medicine …, 2020 - iopscience.iop.org
Proton computed tomography (pCT) promises to reduce or even eliminate range
uncertainties inherent in the conversion of Hounsfield units into relative stopping power …

Proof of concept image artifact reduction by energy-modulated proton computed tomography (EMpCT)

J Dickmann, C Sarosiek, V Rykalin, M Pankuch… - Physica Medica, 2021 - Elsevier
Purpose To reduce imaging artifacts and improve image quality of a specific proton
computed tomography (pCT) prototype scanner by combining pCT data acquired at two …

Helium radiography with a digital tracking calorimeter—a Monte Carlo study for secondary track rejection

HES Pettersen, L Volz, JR Sølie, J Alme… - Physics in Medicine …, 2021 - iopscience.iop.org
Radiation therapy using protons and heavier ions is a fast-growing therapeutic option for
cancer patients. A clinical system for particle imaging in particle therapy would enable online …

Investigating particle track topology for range telescopes in particle radiography using convolutional neural networks

HES Pettersen, M Aehle, J Alme, GG Barnaföldi… - Acta …, 2021 - Taylor & Francis
Background Proton computed tomography (pCT) and radiography (pRad) are proposed
modalities for improved treatment plan accuracy and in situ treatment validation in proton …