Biological utility of fluorinated compounds: from materials design to molecular imaging, therapeutics and environmental remediation

C Zhang, K Yan, C Fu, H Peng, CJ Hawker… - Chemical …, 2021 - ACS Publications
The applications of fluorinated molecules in bioengineering and nanotechnology are
expanding rapidly with the controlled introduction of fluorine being broadly studied due to …

Cyclotriphosphazene based materials: Structure, functionalization and applications

D Wang, X Xu, Y Qiu, J Wang, L Meng - Progress in Materials Science, 2024 - Elsevier
In recent decades, cyclotriphosphazene (CTP) and its derivatives have garnered significant
attention due to their exceptional physical and chemical properties, such as remarkable …

Ultra-stable all-solid-state sodium metal batteries enabled by perfluoropolyether-based electrolytes

X Wang, C Zhang, M Sawczyk, J Sun, Q Yuan… - Nature Materials, 2022 - nature.com
Rechargeable batteries paired with sodium metal anodes are considered to be one of the
most promising high-energy and low-cost energy-storage systems. However, the use of …

Fluorine in medicinal chemistry: in perspective to COVID-19

C Zhang - ACS omega, 2022 - ACS Publications
Over two years into the outbreak of COVID-19, the quest for effective and economical drugs
has become starkly clear to reduce the risk of progression of coronavirus disease. A number …

High F-Content Perfluoropolyether-Based Nanoparticles for Targeted Detection of Breast Cancer by 19F Magnetic Resonance and Optical Imaging

C Zhang, SS Moonshi, W Wang, HT Ta, Y Han… - ACS …, 2018 - ACS Publications
Two important challenges in the field of 19F magnetic resonance imaging (MRI) are the
maintenance of high fluorine content without compromising imaging performance, and …

Integrating Fluorinated Polymer and Manganese‐Layered Double Hydroxide Nanoparticles as pH‐activated 19F MRI Agents for Specific and Sensitive Detection of …

C Zhang, L Li, FY Han, X Yu, X Tan, C Fu, ZP Xu… - Small, 2019 - Wiley Online Library
Abstract 19F magnetic resonance imaging (19F MRI) agents capable of being activated
upon interactions with cancer triggers are attracting increasing attention, although …

Functional polymers as metal-free magnetic resonance imaging contrast agents

C Fu, Y Yu, X Xu, Q Wang, Y Chang, C Zhang… - Progress in Polymer …, 2020 - Elsevier
Magnetic resonance imaging (MRI) is recognized as the most powerful clinical imaging
modality due to its ability to generate detailed three-dimensional anatomical images with …

Tuning of the aggregation behavior of fluorinated polymeric nanoparticles for improved therapeutic efficacy

C Zhang, T Liu, W Wang, CA Bell, Y Han, C Fu… - ACS …, 2020 - ACS Publications
Incorporation of fluorinated moieties in polymeric nanoparticles has been shown in many
instances to increase their uptake by living cells and, hence, has proven to be a useful …

A unique 19 F MRI agent for the tracking of non phagocytic cells in vivo

SS Moonshi, C Zhang, H Peng, S Puttick, S Rose… - Nanoscale, 2018 - pubs.rsc.org
There is currently intense interest in new methods for understanding the fate of
therapeutically-relevant cells, such as mesenchymal stem cells (MSCs). The absence of a …

Importance of Thermally Induced Aggregation on 19F Magnetic Resonance Imaging of Perfluoropolyether-Based Comb-Shaped Poly(2-oxazoline)s

C Zhang, RJP Sanchez, C Fu… - …, 2018 - ACS Publications
An understanding of thermally induced aggregation and consequent 19F magnetic
resonance imaging (MRI) performance is essential for improved design of thermoresponsive …