Covering: up to June 2017 Natural products and endogenous metabolites engage specific
targets within tissues and cells through complex mechanisms. This review examines the …

Drimane and coloratane sesquiterpenoids are present in several plants, microorganisms,
and marine life. Because of their cytotoxic activity, these sesquiterpenoids have received …

Background: Tectaria coadunata (T. coadunata) is an important fern species with a number
of medicinal properties. It has been evidently found for its effectiveness in ethanomedicinal …

The current study represents the first comprehensive investigation into the general
antifouling activities of the natural drimane sesquiterpene polygodial. Previous studies have …

Parasitic helminths continue to pose problems in human and veterinary medicine, as well as
in agriculture. Resistance to current anthelmintics has prompted the search for new drugs …

Melanoma is a highly invasive cancer that resists most conventional treatments. Therefore,
there is an urgent need to identify alternative anticancer agents able to affect new molecular …

Cell division cycle phosphatases CDC25 A, B and C are involved in modulating cell cycle
processes and are found overexpressed in a large panel of cancer typology. Here, we …

Warburgia ugandensis Sprague (W. ugandensis), widely distributed in Africa, is a traditional
medicinal plant used for the treatment of various diseases including cancer. We intended to …

Simple Summary Prostate cancer (PCa) is the second leading cause of cancer death in men
in the United States. The emergence of resistance to androgen deprivation therapy results in …

The first and stereoselective synthesis of xylodonin A and 22-hydroxyxylodonin A, two
drimane-type sesquiterpenoid natural products, was developed from the readily available …