In the pharmaceutical industry, the unexpected appearance of crystalline forms could impact the therapeutic efficacy of an Active Pharmaceutical Ingredient (API). For quality control, a …
V Štrukil, MD Igrc, L Fábián, M Eckert-Maksić… - Green chemistry, 2012 - pubs.rsc.org
The mechanochemical click coupling of isothiocyanates and amines has been used as a model reaction to demonstrate that the concept of a solvent-free research laboratory, which …
The occurrence of tautomeric polymorphism in the Cambridge Structural Database (CSD) was established to be very rare in a previous study by AJ Cruz-Cabeza and CR Groom …
S Góbi, I Reva, G Ragupathy, R Fausto… - The Journal of …, 2024 - ACS Publications
Amorphous thioacetamide (TA) ice was prepared by deposition on a low-temperature substrate in an ultrahigh-vacuum simulation chamber, exposing the sample to a beam of …
Performing reactions in the solid state offers the largely unexplored possibility of influencing reactivity by manipulating the solid form of the starting reactants. In this work, we explore the …
V Stilinovic, B Kaitner - Crystal growth & design, 2012 - ACS Publications
A series of 22 salts and co-crystals of gentisic acid and pyridine derivatives were synthesized and their crystal structures were studied by X-ray diffraction. The proton transfer …
This work presents a successful application of a recently reported supramolecular strategy for stabilization of metastable tautomers in cocrystals to monocomponent, non‐heterocyclic …
N-Salicylideneaniline (SA) and its derivatives are known to possess chromism upon exposure to external stimuli. Herein, we present mechanochemical synthesis of a series of …
F Chen, Y Ma, Y Wang, L Qi - Crystal Growth & Design, 2018 - ACS Publications
Tautomeric isomerism is very important in DNA/RNA research, especially base-pair mismatches. However, the tautomeric polymorph of anhydrous guanine (AG) composed of a …