Cardiovascular disease is the most common cause of death worldwide, especially beyond
the age of 65 years, with the vast majority of morbidity and mortality due to myocardial …

The GCN5-related N-acetyltransferase (GNAT) superfamily of proteins, widespread in
eukaryotes and prokaryotes, can utilize acyl coenzyme A (acyl CoA) to acylate respective …

Septic shock is a life‐threatening clinical condition characterized by a robust immune
inflammatory response to disseminated infection. Little is known about its impact on the …

Mood-related disorders have a high prevalence among children and adolescents, posing a
public health challenge, given their adverse impact on these young populations. Treatment …

Primary hepatocytes are widely utilized for investigating drug efficacy and toxicity, yet
variations between batches and limited proliferation capacity present significant challenges …

Spinal cord injury (SCI) denotes damage to both the structure and function of the spinal cord,
primarily manifesting as sensory and motor deficits caused by disruptions in neural …

Ligation of both the T-cell receptor (TCR) and the CD28 receptor is required for full T-cell
activation to occur. Engagement of the TCR in primary T cells is followed by rapid cAMP …

Ethnopharmacological relevance First recorded in “Sheng Nong's herbal classic”, Paris
polyphylla is used to treat diseases, such as convulsions, head shaking and tongue fiddling …

Background A hallmark of heart failure is cardiac fibrosis, which results from the injury‐
induced differentiation response of resident fibroblasts to myofibroblasts that deposit …

Ovarian cancer is one of the most heterogeneous malignancies in the field of gynecologic
oncology. Deregulation of long noncoding RNAs (lncRNAs) is implicated in carcinogenesis …