Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Despite the ability of peripheral nerves to spontaneously regenerate after injury, recovery is
generally very poor. The neurotrophins have emerged as an important modulator of axon …

Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has pleiotropic effects on
neuronal morphology and synaptic plasticity that underlie hippocampal circuit development …

Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a key role in the
central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection …

The growing incidence of neurodegenerative disorders in our populations is leading the
research to identify potential biomarkers and targets for facilitating their early management …

Abstract Brain Derived Neurotrophic Factor (BDNF) signalling contributes to the formation,
maturation and plasticity of Central Nervous System (CNS) synapses. Acute exposure of …

Background A parallel downregulation of brain-derived neurotrophic factor (BDNF) and
somatostatin (SST), a marker of inhibitory gamma-aminobutyric acid interneurons that target …

Alternative processing of nascent mRNAs is widespread in eukaryotic organisms and greatly
impacts the output of gene expression. Specifically, alternative cleavage and …

The neurotrophin brain‐derived neurotrophic factor (BDNF) plays multiple roles in the
nervous system, including in neuronal development, in long‐term synaptic potentiation in …

Brain-derived neurotrophic factor (BDNF) promotes neuronal survival and growth during
development. In the adult nervous system, BDNF is important for synaptic function in several …