[HTML][HTML] Defining the risk of SARS-CoV-2 variants on immune protection
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
[HTML][HTML] Quantification of SARS-CoV-2 neutralizing antibody by wild-type plaque reduction neutralization, microneutralization and pseudotyped virus neutralization …
KR Bewley, NS Coombes, L Gagnon, L McInroy… - Nature protocols, 2021 - nature.com
Virus neutralization assays measure neutralizing antibodies in serum and plasma, and the
plaque reduction neutralization test (PRNT) is considered the gold standard for measuring …
plaque reduction neutralization test (PRNT) is considered the gold standard for measuring …
Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants
A Pegu, SE O'Connell, SD Schmidt, S O'Dell… - Science, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations may diminish
vaccine-induced protective immune responses, particularly as antibody titers wane over …
vaccine-induced protective immune responses, particularly as antibody titers wane over …
[HTML][HTML] Systems vaccinology of the BNT162b2 mRNA vaccine in humans
The emergency use authorization of two mRNA vaccines in less than a year from the
emergence of SARS-CoV-2 represents a landmark in vaccinology,. Yet, how mRNA …
emergence of SARS-CoV-2 represents a landmark in vaccinology,. Yet, how mRNA …
[HTML][HTML] Infection and vaccine-induced neutralizing-antibody responses to the SARS-CoV-2 B. 1.617 variants
Neutralizing Activity against SARS-CoV-2 Variants Among samples obtained from persons
who had received the mRNA-1273 or BNT162b2 vaccines, neutralizing antibody titers …
who had received the mRNA-1273 or BNT162b2 vaccines, neutralizing antibody titers …
[PDF][PDF] Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells
Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we
evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based …
evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based …
[PDF][PDF] mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron
M Gagne, JI Moliva, KE Foulds, SF Andrew, BJ Flynn… - Cell, 2022 - cell.com
SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …
[PDF][PDF] mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant
emerged in November 2021 and consists of several mutations within the spike. We use …
emerged in November 2021 and consists of several mutations within the spike. We use …
[HTML][HTML] Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
PS Arunachalam, AC Walls, N Golden, C Atyeo… - Nature, 2021 - nature.com
The development of a portfolio of COVID-19 vaccines to vaccinate the global population
remains an urgent public health imperative. Here we demonstrate the capacity of a subunit …
remains an urgent public health imperative. Here we demonstrate the capacity of a subunit …
Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates
INTRODUCTION Mass vaccination against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) offers the most efficient public health intervention to control the COVID-19 …
(SARS-CoV-2) offers the most efficient public health intervention to control the COVID-19 …