Recent advance in the sensing of biomarker transcription factors

B Li, S Xie, A Xia, T Suo, H Huang, X Zhang… - TrAC Trends in …, 2020 - Elsevier
Transcription factors (TFs) are sequence-specific DNA binding proteins functioned as the
key regulators of cell fate and progress. The association between TFs and their binding sites …

Kaleidoscope megamolecules synthesis and application using self-assembly technology

S Zhou, Y Wei - Biotechnology Advances, 2023 - Elsevier
The megamolecules with high ordered structures play an important role in chemical biology
and biomedical engineering. Self-assembly, a long-discovered but very appealing …

Strategy based on multiplexed brush architectures for regulating the spatiotemporal immobilization of biomolecules

H Zhao, T Chen, T Wu, L Xie, Y Ma, J Sha - Biomaterials Advances, 2022 - Elsevier
Functional surfaces that enable both spatial and temporal control of biomolecules
immobilization have attracted enormous attention for various fields including smart …

UV-and Visible-Light Photopatterning of Molecular Gradients Using the Thiol–yne Click Reaction

M Mitmoen, O Kedem - ACS Applied Materials & Interfaces, 2022 - ACS Publications
The rational design of chemical coatings is used to control surface interactions with small
molecules, biomolecules, nanoparticles, and liquids as well as optical and other properties …

Solid-phase synthesis of megamolecules

BR Kimmel, JA Modica, K Parker… - Journal of the …, 2020 - ACS Publications
This paper presents a solid-phase strategy to efficiently assemble multiprotein scaffolds—
known as megamolecules—without the need for protecting groups and with precisely …

Construction of homologous branched oligomer megamolecules based on linker-directed protein assembly

Y Chen, H Feng, L Chen, W Zhou, S Zhou - Soft Matter, 2024 - pubs.rsc.org
Utilizing the building blocks of recombinant proteins and synthetic linkers, we have obtained
two distinct octameric megamolecules with diverse branched structures. This approach …

Analysis of actin and focal adhesion organisation in U2OS cells on polymer nanostructures

JB Vinje, NA Guadagno, C Progida… - Nanoscale Research …, 2021 - Springer
Background In this work, we explore how U2OS cells are affected by arrays of polymer
nanopillars fabricated on flat glass surfaces. We focus on describing changes to the …

Patterned organic layers on gold surfaces prepared by electro-grafting of photolabile-protected aryl diazonium salts

M Taras, JF Bergamini, PA Brooksby, P Hapiot… - RSC Applied …, 2024 - pubs.rsc.org
The electroreduction of aryl diazonium salts is a powerful technique for functionalizing many
surfaces. To widen the use of aryl diazonium salts in many more applications, new strategies …

Development of an Enzyme‐Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One‐Pot Megamolecule Assembly

BR Kimmel, M Mrksich - Chemistry–A European Journal, 2021 - Wiley Online Library
This paper presents an enzyme building block for the assembly of megamolecules. The
system is based on the inhibition of the human‐derived cellular retinoic acid binding protein …

Antibody Printing Technologies

V Romanov, BD Brooks - Antibody Arrays: Methods and Protocols, 2021 - Springer
Antibody microarrays are routinely employed in the lab and in the clinic for studying protein
expression, protein-protein, and protein-drug interactions. The microarray format reduces …