Posttranslational modification of proteins often controls various aspects of their cellular
function. Indeed, over the past decade or so, it has been discovered that posttranslational …

Human neurodegenerative and infectious diseases and tumorigenesis are associated with
alterations in ubiquitin pathways. Over 10% of the genome encode for genes that either bind …

This review describes some of the more interesting and imaginative ways in which mass
spectrometry has been utilized to study a number of important post‐translational …

Small ubiquitin‐like modifier (SUMO1–3) conjugation is a posttranslational protein
modification whereby SUMOs are conjugated to lysine residues of target proteins. SUMO …

SUMOylation is a protein posttranslational modification that participates in the regulation of
numerous biological processes within the cells. Small ubiquitin-like modifier (SUMO) …

Protein modification by ubiquitination and SUMOylation occur throughout the cell and are
responsible for numerous cellular functions such as apoptosis, DNA replication and repair …

SUMOylation is a post-translational modification that plays critical roles in a multitude of
cellular processes including transcription, cellular localization, DNA repair and cell cycle …

A variety of cellular pathways are regulated by protein modifications with ubiquitin-family
proteins. SUMO, the S mall U biquitin-like MO difier, is covalently attached to lysine on target …

SUMO is a small post-translational modifier, that is attached to lysine residues in target
proteins. It acts by altering protein-protein interactions, protein localisation and protein …

Multiple studies demonstrate that ubiquitination of proteins codes for regulation of cell
differentiation, apoptosis, endocytosis and many other cellular functions. There is great …