Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy
BRH Van den Bergh, MI van den Heuvel… - Neuroscience & …, 2020 - Elsevier
Accumulating research shows that prenatal exposure to maternal stress increases the risk
for behavioral and mental health problems later in life. This review systematically analyzes …
for behavioral and mental health problems later in life. This review systematically analyzes …
Changes in the maternal hypothalamic-pituitary-adrenal axis in pregnancy and postpartum: influences on maternal and fetal outcomes
L Duthie, RM Reynolds - Neuroendocrinology, 2013 - karger.com
Overexposure of the developing fetus to glucocorticoids is hypothesised to be one of the key
mechanisms linking early life development with later life disease. The maternal …
mechanisms linking early life development with later life disease. The maternal …
Epigenetic inheritance: concepts, mechanisms and perspectives
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …
conditions, including psychopathologies, and their effects may even endure for several …
Prenatal stress and its effects on the fetus and the child: possible underlying biological mechanisms
V Glover - Perinatal programming of neurodevelopment, 2015 - Springer
Many prospective studies have shown that if a mother is depressed, anxious or stressed
while pregnant, this increases the risk for her child having a wide range of adverse …
while pregnant, this increases the risk for her child having a wide range of adverse …
Prenatal stress and epigenetics
In utero exposure to environmental stress in both animals and humans could result in long-
term epigenome alterations which further lead to consequences for adaptation and …
term epigenome alterations which further lead to consequences for adaptation and …
Maternal prenatal anxiety and downregulation of placental 11β-HSD2
KJ O'Donnell, AB Jensen, L Freeman, N Khalife… - …, 2012 - Elsevier
BACKGROUND: Raised maternal anxiety during pregnancy is associated with increased
risk of adverse neurodevelopmental outcomes for her child. The mechanisms underlying this …
risk of adverse neurodevelopmental outcomes for her child. The mechanisms underlying this …
The placenta as a mediator of stress effects on neurodevelopmental reprogramming
SL Bronson, TL Bale - Neuropsychopharmacology, 2016 - nature.com
Adversity experienced during gestation is a predictor of lifetime neuropsychiatric disease
susceptibility. Specifically, maternal stress during pregnancy predisposes offspring to sex …
susceptibility. Specifically, maternal stress during pregnancy predisposes offspring to sex …
The roles of DNA methylation of NR3C1 and 11β-HSD2 and exposure to maternal mood disorder in utero on newborn neurobehavior
Exposure to maternal mood disorder in utero may program infant neurobehavior via DNA
methylation of the glucocorticoid receptor (NR3C1) and 11β-hydroxysteroid dehydrogenase …
methylation of the glucocorticoid receptor (NR3C1) and 11β-hydroxysteroid dehydrogenase …
Epigenetic programming by early‐life stress: Evidence from human populations
AM Vaiserman - Developmental Dynamics, 2015 - Wiley Online Library
Background: A substantial body of experimental and epidemiological evidence has been
accumulated suggesting that stressful events in early life including acute perinatal stress …
accumulated suggesting that stressful events in early life including acute perinatal stress …
Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome
Background There is growing evidence that the intrauterine environment can impact the
neurodevelopment of the fetus through alterations in the functional epigenome of the …
neurodevelopment of the fetus through alterations in the functional epigenome of the …