Approaches to prevent and manage cardiovascular disease in patients receiving therapy for prostate cancer

CT Ng, HMG Bonilla, AH Bryce, P Singh… - Current cardiology …, 2023 - Springer
Abstract Purpose of Review Prostate cancer (PCa) is amongst the most common cancers in
men worldwide. Cardiovascular (CV) risk factors and CV disease (CVD) are common …

Sex differences in the cardiovascular effects of GnRH analogues

MWS Lim, AK Lucas-Herald, A Mason… - Journal of …, 2024 - joe.bioscientifica.com
The integral role of the hypothalamic–pituitary–gonadal axis in reproductive processes
makes it a prime therapeutic target. By inhibiting sex steroid synthesis, gonadotropin …

Association of frailty with the incidence risk of cardiovascular disease and type 2 diabetes mellitus in long-term cancer survivors: a prospective cohort study

X Cao, Z Yang, X Li, C Chen, EO Hoogendijk, J Zhang… - BMC medicine, 2023 - Springer
Background Comorbidities among cancer survivors remain a serious healthcare burden and
require appropriate management. Using two widely used frailty indicators, this study aimed …

Cardiovascular risk profiles of GnRH agonists and antagonists: real-world analysis from UK general practice

P Davey, MG Kirby - World Journal of Urology, 2021 - Springer
Purpose Androgen deprivation therapy (ADT) is the mainstay for the management of
metastatic prostate cancer. Available pharmaceutical ADTs include gonadotropin-releasing …

Gonadotropin‐releasing hormone antagonist associated with lower cardiovascular risk compared with gonadotropin‐releasing hormone agonist in prostate cancer: A …

DY Chen, PJ Su, LC See, JR Liu, CK Chuang… - The …, 2021 - Wiley Online Library
Background We aimed to determine whether cardiovascular (CV) risk in patients with
prostate cancer (PCa) differs between those who receive gonadotropin‐releasing hormone …

Use of new and emerging cancer drugs: what the cardiologist needs to know

I Fabiani, M Chianca, A Aimo, M Emdin… - European Heart …, 2024 - academic.oup.com
The last decade has witnessed a paradigm shift in cancer therapy, from non-specific
cytotoxic chemotherapies to agents targeting specific molecular mechanisms. Nonetheless …

Cardiovascular risk of gonadotropin-releasing hormone antagonist versus agonist in men with prostate cancer: an observational study in Taiwan

YHJ Shao, JH Hong, CK Chen… - Prostate Cancer and …, 2023 - nature.com
Background The impact of gonadotropin-releasing hormone (GnRH) antagonist and agonist
(GnRHa) treatment on cardiovascular disease (CVD) risk in prostate cancer (PCa) remains …

Risk of ischemic heart disease and stroke in prostate cancer survivors: a nationwide study in South Korea

DW Shin, K Han, HS Park, SP Lee, SH Park, J Park - Scientific reports, 2020 - nature.com
In this study using national health insurance data, we investigated the risk of ischemic heart
disease (IHD) and stroke among prostate cancer (PC) survivors compared with the general …

Endothelial dysfunction after androgen deprivation therapy and the possible underlying mechanisms

JYC Teoh, XY Tian, CYP Wong, CW Lau… - The …, 2022 - Wiley Online Library
Introduction Androgen deprivation therapy (ADT) is a key treatment modality in the
management of prostate cancer (PCa), especially for patients with metastatic disease …

Assessment and mitigation of cardiovascular risk for prostate cancer patients: a review of the evidence

P Davey, K Alexandrou - International Journal of Clinical …, 2022 - Wiley Online Library
Background. Cardiovascular disease (CVD) is a common comorbidity in patients with
prostate cancer. In this review, we summarize the published literature on the association of …