Low-intensity focused ultrasound for human neuromodulation
W Legon, A Strohman - Nature Reviews Methods Primers, 2024 - nature.com
Low-intensity focused ultrasound (LIFU) is a potentially transformative form of human non-
invasive neuromodulation that provides millimetre-sized focal volumes combined with …
invasive neuromodulation that provides millimetre-sized focal volumes combined with …
Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans
Transcranial ultrasonic stimulation (TUS) is rapidly emerging as a promising non-invasive
neuromodulation technique. TUS is already well-established in animal models, providing …
neuromodulation technique. TUS is already well-established in animal models, providing …
[HTML][HTML] A practical guide to transcranial ultrasonic stimulation from the IFCN-endorsed ITRUSST Consortium
KR Murphy, T Nandi, B Kop, T Osada, M Lueckel… - Clinical …, 2025 - Elsevier
Abstract Low-intensity Transcranial Ultrasonic Stimulation (TUS) is a non-invasive brain
stimulation technique enabling cortical and deep brain targeting with unprecedented spatial …
stimulation technique enabling cortical and deep brain targeting with unprecedented spatial …
[HTML][HTML] Low-intensity focused ultrasound to the posterior insula reduces temporal summation of pain
A In, A Strohman, B Payne, W Legon - Brain stimulation, 2024 - Elsevier
Background The insula and dorsal anterior cingulate cortex (dACC) are core brain regions
involved in pain processing and central sensitization, a shared mechanism across various …
involved in pain processing and central sensitization, a shared mechanism across various …
[HTML][HTML] Ultrasound modulates neuronal potassium currents via ionotropic glutamate receptors
B Clennell, TGJ Steward, K Hanman, T Needham… - Brain Stimulation, 2023 - Elsevier
Background Focused ultrasound stimulation (FUS) has the potential to provide non-invasive
neuromodulation of deep brain regions with unparalleled spatial precision. However, the …
neuromodulation of deep brain regions with unparalleled spatial precision. However, the …
Transcranial focused ultrasound to V5 enhances human visual motion brain-computer interface by modulating feature-based attention
A brain-computer interface (BCI) enables users to control devices with their minds. Despite
advancements, non-invasive BCIs still exhibit high error rates, prompting investigation into …
advancements, non-invasive BCIs still exhibit high error rates, prompting investigation into …
[HTML][HTML] Neuromodulation techniques–From non-invasive brain stimulation to deep brain stimulation
Over the past 30 years, the field of neuromodulation has witnessed remarkable
advancements. These developments encompass a spectrum of techniques, both non …
advancements. These developments encompass a spectrum of techniques, both non …
A review of functional neuromodulation in humans using low-intensity transcranial focused ultrasound
Transcranial ultrasonic neuromodulation is a rapidly burgeoning field where low-intensity
transcranial focused ultrasound (tFUS), with exquisite spatial resolution and deep tissue …
transcranial focused ultrasound (tFUS), with exquisite spatial resolution and deep tissue …
[HTML][HTML] Early-phase neuroplasticity induced by offline transcranial ultrasound stimulation in primates
N Bault, SN Yaakub, E Fouragnan - Current Opinion in Behavioral Sciences, 2024 - Elsevier
Highlights•TUS can induce neural and behavioural changes in primates outlasting the
sonication.•Both local and widespread changes in brain activity following TUS have been …
sonication.•Both local and widespread changes in brain activity following TUS have been …
Transcranial focused ultrasound-induced blood‒brain barrier opening in mice without shaving hairs
Acoustic coupling through hairs remains a challenge to performing transcranial-focused
ultrasound procedures. Here, we demonstrated that this challenge could be addressed by …
ultrasound procedures. Here, we demonstrated that this challenge could be addressed by …