Biginelli reaction: an overview

H Nagarajaiah, A Mukhopadhyay, JN Moorthy - Tetrahedron Letters, 2016 - Elsevier
Biginelli reaction involves acid-catalyzed one-pot synthesis of 3, 4-dihydropyrimidin-2 (1 H)-
ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active …

Molecular iodine-catalyzed multicomponent reactions: an efficient catalyst for organic synthesis

YM Ren, C Cai, RC Yang - RSC advances, 2013 - pubs.rsc.org
The multicomponent reactions (MCRs) consist of two or more synthetic steps which are
carried out without isolation of any intermediate thus reducing time, saving money, energy …

Indium (III) chloride-catalyzed one-pot synthesis of dihydropyrimidinones by a three-component coupling of 1, 3-dicarbonyl compounds, aldehydes, and urea: an …

BC Ranu, A Hajra, U Jana - Journal of Organic Chemistry, 2000 - organic-chemistry.org
An indium (III) chloride catalyzed Biginelli reaction of 1, 3-dicarbonyl compounds,
aldehydes, and ureas offers an easy access to a broad range of dihydropyrimidin-2 (1H) …

Silica sulfuric acid: an efficient and reusable catalyst for the one-pot synthesis of 3, 4-dihydropyrimidin-2 (1H)-ones

P Salehi, M Dabiri, MA Zolfigol, MAB Fard - Tetrahedron Letters, 2003 - Elsevier
Silica sulfuric acid efficiently catalyzes the three-component Biginelli reaction between an
aldehyde, a β-dicarbonyl compound and urea or thiourea in refluxing ethanol to afford the …

One-pot synthesis of 3, 4-dihydropyrimidin-2 (1H)-ones using lanthanum chloride as a catalyst

J Lu, Y Bai, Z Wang, B Yang, H Ma - Tetrahedron Letters, 2000 - Elsevier
An efficient synthesis of 3, 4-dihydropyrimidinones using lanthanum chloride heptahydrate
as a catalyst from an aldehyde, β-keto ester and urea or thiourea in ethanol is described …

Green Chemistry Approaches to the Synthesis of 5-Alkoxycarbonyl-4-aryl-3,4- dihydropyrimidin-2(1H)-ones by a Three-Component Coupling of One-Pot …

DS Bose, L Fatima, HB Mereyala - The Journal of organic …, 2003 - ACS Publications
A general and practical green chemistry route to the Biginelli cyclocondensation reaction
using cerium (III) chloride as the catalyst (25% mol) is described under three different sets of …

[HTML][HTML] An efficient synthesis of 3, 4-dihydropyrimidin-2-ones catalyzed by NH2SO3H under ultrasound irradiation

JT Li, JF Han, JH Yang, TS Li - Ultrasonics Sonochemistry, 2003 - Elsevier
An efficient synthesis of 3,4-dihydropyrimidin-2-ones catalyzed by NH2SO3H under ultrasound
irradiation - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …

Catalysis of the Biginelli reaction by ferric and nickel chloride hexahydrates. One-pot synthesis of 3, 4-dihydropyrimidin-2 (1H)-ones

J Lu, Y Bai - Synthesis, 2002 - thieme-connect.com
Abstract An efficient synthesis of 3, 4-dihydropyrimidinones from the aldehyde, β-keto ester
and urea in ethanol, using ferric chloride hexahydrate or nickel chloride hexahydrate as the …

Ammonium chloride-catalyzed one-pot synthesis of 3, 4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions

A Shaabani, A Bazgir, F Teimouri - Tetrahedron Letters, 2003 - Elsevier
Ammonium chloride as a very inexpensive and readily available reagent, and efficiently
catalyzes one-pot, three component, Biginelli condensation reactions of aldehydes, 1, 3 …

The B iginelli Dihydropyrimidine Synthesis

CO Kappe, A Stadler - Organic reactions, 2004 - Wiley Online Library
The cyclocondensation of suitable CH‐acidic carbonyl compounds, aldehydes, and urea‐
type blocks under acidic conditions provides multifunctionalized derivatives. The discovery …