Cancer is a severe public health issue that is a leading cause of mortality globally. It is also
an impediment to improving life expectancy worldwide. Furthermore, the global burden of …

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …

Cancer stem cells drive tumor initiation, progression, and recurrence, which compromise the
effectiveness of anti-tumor drugs. Here, we report that demethylzeylasteral (DML), a …

Simple Summary Vimentin is an important filamentous protein providing structural and
functional support to the cell. During initial stages of cancer development, vimentin …

Abstract Caspase‐3, a cysteine‐aspartic acid protease, has recently attracted much
attention because of its incredible roles in tissue differentiation, regeneration, and neural …

For over three decades, a mainstay and goal of clinical oncology has been the development
of therapies promoting the effective elimination of cancer cells by apoptosis. This …

Tumor resistance to apoptosis and the immunosuppressive tumor microenvironment are two
major contributors to poor therapeutic responses during cancer intervention. Pyroptosis, a …

With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

Cancer is the second leading cause of death in the world and one of the major public health
problems. Despite the great advances in cancer therapy, the incidence and mortality rates of …

Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …