Selected flavonols in breast and gynecological cancer: a systematic review

D Wendlocha, K Krzykawski, A Mielczarek-Palacz… - Nutrients, 2023 - mdpi.com
The consumption of foods that are rich in phenolic compounds has chemopreventive effects
on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide …

Antiviral and possible prophylactic significance of myricetin for COVID-19

PK Agrawal, C Agrawal… - Natural Product …, 2023 - journals.sagepub.com
Myricetin (3, 5, 7, 3′, 4′, 5′-hexahydroxyflavone), a common dietary flavonoid, has been
reported for its roles in improving health due to various pharmacological activities, such as …

Naringin ameliorates 5-fluorouracil induced cardiotoxicity: An insight into its modulatory impact on oxidative stress, inflammatory and apoptotic parameters

Y Gui, AC Famurewa, OJ Olatunji - Tissue and Cell, 2023 - Elsevier
fluorouracil (5-FU) is an efficacious fluoropyrimidine antimetabolite anticancer drug,
however, its clinical utility is constrained due to side effect toxicity on delicate organs …

A rodent model of human-dose-equivalent 5-fluorouracil: toxicity in the liver, kidneys, and lungs

MC da Silva, LC Fabiano, KC da Costa Salomão… - Antioxidants, 2023 - mdpi.com
5-Fluorouracil (5-FU) is a chemotherapy drug widely used to treat a range of cancer types,
despite the recurrence of adverse reactions. Therefore, information on its side effects when …

Geraniol ameliorates doxorubicin-mediated kidney injury through alteration of antioxidant status, inflammation, and apoptosis: potential roles of NF-κB and Nrf2/Ho-1

AF AlAsmari, N Ali, M Alharbi, F Alqahtani, F Alasmari… - Nutrients, 2022 - mdpi.com
Doxorubicin-mediated kidney impairment is a serious problem in cancer treatment.
Accordingly, this work investigated the ability of geraniol to modulate doxorubicin-induced …

Myricetin: a potential plant-derived anticancer bioactive compound—an updated overview

S Kumar, N Swamy, HS Tuli, S Rani, A Garg… - Naunyn-Schmiedeberg's …, 2023 - Springer
The globe is currently confronting a global fight against the deadliest cancer sickness.
Chemotherapy, hormonal therapy, surgery, and radiation therapy are among cancer …

Zerumbone protects rats from collagen-induced arthritis by inhibiting oxidative outbursts and inflammatory cytokine levels

RM Alsaffar, A Ali, SM Rashid, SB Ahmad… - Acs Omega, 2023 - ACS Publications
Rheumatoid arthritis (RA) is an immunocompromised disorder characterized by a marked
increase in the synthesis of inflammatory molecules that stimulates the destruction of bones …

A novel drug–drug cocrystal of tegafur and myricetin: optimized properties of dissolution and tabletability

M Zhang, DL Gu, JF Zhen, TB Lu, XL Dai, JM Chen - CrystEngComm, 2023 - pubs.rsc.org
Tegafur (TGF) is a broad-spectrum anti-tumor drug, but it suffers from fast metabolism and
consequently poor oral absorption. Myricetin (MYR) is a flavonoid with anti-tumor activity …

Exotic god fruit, persimmon (Diospyros kaki): Pharmacological importance and human health aspects

R Choudhary, A Singh, A Upadhyay, R Singh… - eFood, 2023 - Wiley Online Library
The persimmon fruit (Diospyros kaki) belonging to the family Ebenaceae, is a famous
conventional Korean medicinal herb. Calyx of persimmon has been used to prepare herbal …

Cardioprotective potential of mitochondria-targeted antioxidant, mito-TEMPO, in 5-fluorouracil-induced cardiotoxicity

PK Tambe, AJ Mathew, S Bharati - Cancer Chemotherapy and …, 2023 - Springer
Purpose The mitochondria-targeted antioxidants (MTAs) are known to offer protection
against mitochondrial oxidative stress. The recent evidences support their role in mitigating …