The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …

The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our
understanding of vasculogenesis and angiogenesis during development and physiological …

Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …

The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

Background Retinal ischemia induces intraocular neovascularization, which often leads to
glaucoma, vitreous hemorrhage, and retinal detachment, presumably by stimulating the …

Biology of Vascular Endothelial Growth Factor | Endocrine Reviews | Oxford Academic Skip to
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THE development of new blood vessels (angiogenesis) is required for many physiological
processes including embryogenesis, wound healing and corpus luteum formation1, 2. Blood …

Vascular endothelial growth factor (VEGF) mRNA undergoes alternative splicing events that
generate four different homodimeric isoforms, VEGF121, VEGF165, VEGF189, or VEGF206 …

Vascular endothelial growth factor (VEGF) is a fundamental regulator of normal and
abnormal angiogenesis. Recent evidence indicates that VEGF is essential for embryonic …

The vascular endothelial growth factor (VEGF) family encompasses four polypeptides that
result from alternative splicing of mRNA. We have previously demonstrated differences in …