Applications of serum albumins in delivery systems: Differences in interfacial behaviour and interacting abilities with polysaccharides

A Aguilera-Garrido, T del Castillo-Santaella… - Advances in Colloid and …, 2021 - Elsevier
One of the major applications of Serum Albumins is their use as delivery systems for
lipophilic compounds in biomedicine. Their biomedical application is based on the similarity …

Spectrofluorimetric analysis of the binding of a target molecule to serum albumin: Tricky aspects and tips

F Macii, T Biver - Journal of inorganic biochemistry, 2021 - Elsevier
Protein binding heavily modulates drug activity. Therefore, the binding features need to be
elucidated when chemistry researchers study new molecules (metal complexes) to be used …

Heterostructural Nanoadjuvant CuSe/CoSe2 for Potentiating Ferroptosis and Photoimmunotherapy through Intratumoral Blocked Lactate Efflux

C Yang, M Wang, M Chang, M Yuan… - Journal of the …, 2023 - ACS Publications
The desirable curative effect in clinical immunotherapy has been challenging due to the
immunosuppressive tumor microenvironment (TME) with high lactic acid (LA) metabolism in …

Nanoparticle-mediated inhibition of mitochondrial glutaminolysis to amplify oxidative stress for combination cancer therapy

L Xu, R Xu, PE Saw, J Wu, SX Cheng, X Xu - Nano letters, 2021 - ACS Publications
Selective amplification of reactive oxygen species (ROS) generation in tumor cells has been
recognized as an effective strategy for cancer therapy. However, an abnormal tumor …

Multi-Spectroscopic, thermodynamic and molecular dynamic simulation studies for investigation of interaction of dapagliflozin with bovine serum albumin

MA Abdelaziz, M Shaldam, RA El-Domany… - Spectrochimica Acta Part …, 2022 - Elsevier
Dapagliflozin (DAPA) is a selective sodium-glucose cotransporter-2 inhibitor that reduces
renal glucose reabsorption. The drug has recently become a crucial milestone in the …

Comparison of the interactions of fanetizole with pepsin and trypsin: Spectroscopic and molecular docking approach

Y Yue, Q Tu, Y Guo, Y Wang, Y Xu, Y Zhang… - Journal of Molecular …, 2022 - Elsevier
In this work, the binding affinity of fanetizole with proteases pepsin and trypsin were
investigated by spectroscopy and molecular docking. As a thiazole derivative, the …

Interaction between potassium iodide and bovine serum albumin, ovalbumin and lysozyme under different temperature induction

W Pan, Y Cao, F Gu, Y Gao, H Liao, Z Li, J Yu… - International Journal of …, 2023 - Elsevier
In this study, the interaction between potassium iodide and protein molecules under different
temperature induction was studied, taking potassium iodide (KI) and protein molecules as a …

Intermolecular interaction of fosinopril with bovine serum albumin (BSA): the multi‐spectroscopic and computational investigation

KL Zhou, DQ Pan, YY Lou… - Journal of Molecular …, 2018 - Wiley Online Library
The intermolecular interaction of fosinopril, an angiotensin converting enzyme inhibitor with
bovine serum albumin (BSA), has been investigated in physiological buffer (pH 7.4) by multi …

Influence of antidepressant clomipramine hydrochloride drug on human serum albumin: Spectroscopic study

MA Rub, JM Khan, N Azum, AM Asiri - Journal of Molecular Liquids, 2017 - Elsevier
The interactions of serum albumins with a variety of drugs have expected immense interest
currently owing to their considerable achieve in the biomedical area. In the current study, we …

Elucidating the binding propensity of naphthyl hydroxamic acid to human serum albumin (HSA): multi-spectroscopic and molecular modeling approach

R Agrawal, Y Thakur, M Tripathi, MK Siddiqi… - Journal of Molecular …, 2019 - Elsevier
The association of human serum albumin (HSA) and its interaction with drug and other novel
compound has garnered keen interest in designing and development for new compounds …