RNA structural dynamics as captured by molecular simulations: a comprehensive overview

J Sponer, G Bussi, M Krepl, P Banáš, S Bottaro… - Chemical …, 2018 - ACS Publications
With both catalytic and genetic functions, ribonucleic acid (RNA) is perhaps the most
pluripotent chemical species in molecular biology, and its functions are intimately linked to …

Regulation of pri-MIRNA processing: mechanistic insights into the miRNA homeostasis in plant

J Jodder - Plant Cell Reports, 2021 - Springer
Abstract miRNAs in plant plays crucial role in controlling proper growth, development and
fitness by modulating the expression of their target genes. Therefore to modulate the …

[HTML][HTML] Identification of key sequence features required for microRNA biogenesis in plants

AML Rojas, SI Drusin, U Chorostecki, JL Mateos… - Nature …, 2020 - nature.com
MicroRNAs (miRNAs) are endogenous small RNAs of∼ 21 nt that regulate multiple
biological pathways in multicellular organisms. They derive from longer transcripts that …

[HTML][HTML] Role of salt-bridging interactions in recognition of viral RNA by arginine-rich peptides

L Levintov, H Vashisth - Biophysical Journal, 2021 - cell.com
Interactions between RNA molecules and proteins are critical to many cellular processes
and are implicated in various diseases. The RNA-peptide complexes are good model …

[HTML][HTML] Discovering Structural Motifs in miRNA Precursors from the Viridiplantae Kingdom

J Miskiewicz, M Szachniuk - Molecules, 2018 - mdpi.com
A small non-coding molecule of microRNA (19–24 nt) controls almost every biological
process, including cellular and physiological, of various organisms' lives. The amount of …

The key role of electrostatic interactions in the induced folding in RNA recognition by DCL1-A

L Zhao, IP Suarez, DF Gauto, RM Rasia… - Physical Chemistry …, 2018 - pubs.rsc.org
The intrinsically disordered protein domain DCL1-A is the first report of a complete double
stranded RNA binding domain folding upon binding. DCL1-A recognizes the dsRNA by …

Conformational sampling of the intrinsically disordered dsRBD-1 domain from Arabidopsis thaliana DCL1

IP Suárez, DF Gauto, G Hails, FC Mascali… - Physical Chemistry …, 2018 - pubs.rsc.org
DCL1 is the ribonuclease that carries out miRNA biogenesis in plants. Substrate pri-miRNA
recognition by DCL1 requires two double stranded RNA binding domains located at the C …

Study of the role of Mg2+ in dsRNA processing mechanism by bacterial RNase III through QM/MM simulations

SI Drusin, RM Rasia, DM Moreno - JBIC Journal of Biological Inorganic …, 2020 - Springer
Abstract The ribonuclease III (RNase III) cleaves dsRNA in specific positions generating
mature RNAs. RNase III enzymes play important roles in RNA processing, post …

Estudio bioinformático estructural del reconocimiento de ARN en el procesamiento de miARNs en plantas

SI Drusin - 2019 - notablesdelaciencia.conicet.gov.ar
Los microARN (miARN) son moléculas de ARN pequeñas de 21 nucleótidos de longitud
que se sintetizan en el núcleo por la ARN polimerasa II. En plantas, están involucrados en …

[图书][B] Mutagenesis and functional characterisation of toxin HicA from the HicBA TA system in Burkholderia pseudomallei.

HL Bare - 2017 - search.proquest.com
Four type II toxin-antitoxin (TA) systems were previously identified in Burkholderia
pseudomallei K96243. Type II TA toxins are able to induce cell growth arrest or death by …