Diabetes mellitus is a medical condition characterized by the body's loss of control over
blood sugar. The frequency of diagnosed cases and consequential increases in medical …

Dihydropyrimidinones are heterocycles with a pyrimidine moiety in the ring nucleus, which,
in recent decades, have aroused interest in medicinal chemistry due to alleged versatile …

Thirty derivatives of flavone hydrazone (5–34) had been synthesized through a five-step
reaction and screened for their α-glucosidase inhibition activity. Chalcone 1 was …

Inhibition of α-glucosidase and α-amylase decreases postprandial blood glucose levels and
delays glucose absorption, making it a treatment strategy for type 2 diabetes. This study …

In the present study, a series of 2-amino-4, 6-diarylpyrimidine derivatives was designed,
synthesized, characterized and evaluated for their in vitro α-glucosidase and α-amylase …

In an attempt to find novel, potent α-glucosidase inhibitors, a library of poly-substituted 3-
amino-2, 4-diarylbenzo [4, 5] imidazo [1, 2-a] pyrimidines 3a–ag have been synthesized …

We report herein the synthesis, α‐glucosidase inhibition and docking studies for a series of
3–15 new flavones. A simple nucleophilic substitution reaction takes place between 3 …

The reactivity of aldehydes and ketones carries great potential for multicomponent
heterocyclizations. These reactions are convergent and highly versatile in the development …

This paper presents the efficient high yield synthesis of novel pyridine 2, 4, 6-
tricarbohydrazide derivatives (4a–4i) along with their α-glucosidase, acetylcholinesterase …

In an attempt to find novel α-glucosidase inhibitors, an efficient, straightforward reaction to
synthesize a library of fully substituted 6-amino-pyrazolo [1, 5-a] pyrimidines 3 has been …