Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research

M Ramirez-Garrastacho, C Bajo-Santos, A Line… - British journal of …, 2022 - nature.com
Prostate cancer is a global cancer burden and considerable effort has been made through
the years to identify biomarkers for the disease. Approximately a decade ago, the potential of …

[HTML][HTML] Circulating RNAs in prostate cancer patients

V Mugoni, Y Ciani, C Nardella, F Demichelis - Cancer letters, 2022 - Elsevier
Growing bodies of evidence have demonstrated that the identification of prostate cancer
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …

[HTML][HTML] Adherence to minimal experimental requirements for defining extracellular vesicles and their functions

R Poupardin, M Wolf, D Strunk - Advanced Drug Delivery Reviews, 2021 - Elsevier
Rigorous measures are required to cope with the advance of extracellular vesicle (EV)
research, from 183 studies published in 2012 to 2,309 studies published in 2020. The …

Prostate cancer-derived small extracellular vesicle proteins: the hope in diagnosis, prognosis, and therapeutics

H Chen, B Pang, C Zhou, M Han, J Gong, Y Li… - Journal of …, 2023 - Springer
Current diagnostic tools for prostate cancer (PCa) diagnosis and risk stratification are
insufficient. The hidden onset and poor efficacy of traditional therapies against metastatic …

Current perspectives on clinical use of exosomes as novel biomarkers for cancer diagnosis

X Yi, J Chen, D Huang, S Feng, T Yang, Z Li… - Frontiers in …, 2022 - frontiersin.org
Exosomes are a heterogeneous subset of extracellular vesicles (EVs) that biogenesis from
endosomes. Besides, exosomes contain a variety of molecular cargoes including proteins …

Immunophenotype profile by flow cytometry reveals different subtypes of extracellular vesicles in porcine seminal plasma

I Barranco, A Alvarez-Barrientos, A Parra… - Cell Communication and …, 2024 - Springer
Background Porcine seminal plasma (SP) is endowed with a heterogeneous population of
extracellular vesicles (sEVs). This study evaluated the immunophenotypic profile by high …

Extracellular vesicles in seminal fluid and effects on male reproduction. An overview in farm animals and pets

J Roca, H Rodriguez-Martinez, L Padilla… - Animal Reproduction …, 2022 - Elsevier
Extracellular vesicles (EVs) are lipid bilayer nanovesicles released by most functional cells
to body fluids, containing bioactive molecules, mainly proteins, lipids, and nucleic acids …

Pathogenic and potential therapeutic roles of exosomes derived from immune cells in liver diseases

L Zhou, M Shen, X Fan, Y Liu, L Yang - Frontiers in Immunology, 2022 - frontiersin.org
Liver diseases, such as viral hepatitis, alcoholic hepatitis and cirrhosis, nonalcoholic
steatohepatitis, and hepatocellular carcinoma place a heavy burden on many patients …

Current advances in technologies for single extracellular vesicle analysis and its clinical applications in cancer diagnosis

L Qiu, X Liu, L Zhu, L Luo, N Sun, R Pei - Biosensors, 2023 - mdpi.com
Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic
biomarkers for different cancers, due to their unique physiological and pathological …

Liquid biopsy in diagnosis and prognosis of non-metastatic prostate cancer

AS Rzhevskiy, AY Kapitannikova, DV Butnaru… - Biomedicines, 2022 - mdpi.com
Currently, sensitive and specific methods for the detection and prognosis of early stage PCa
are lacking. To establish the diagnosis and further identify an appropriate treatment strategy …