The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics

L Qian, X Lin, X Gao, RU Khan, JY Liao, S Du… - Chemical …, 2023 - ACS Publications
The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …

Ligand‐installed nanocarriers toward precision therapy

P Mi, H Cabral, K Kataoka - Advanced Materials, 2020 - Wiley Online Library
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

EGFR targeting for cancer therapy: Pharmacology and immunoconjugates with drugs and nanoparticles

E da Silva Santos, KAB Nogueira… - International journal of …, 2021 - Elsevier
The epidermal growth factor receptor (EGFR) belongs to the tyrosine kinase receptors family
and is present in the epithelial cell membrane. Its endogenous activation occurs through the …

Recent trends of the bio-inspired nanoparticles in cancer theranostics

VS Madamsetty, A Mukherjee… - Frontiers in …, 2019 - frontiersin.org
In recent years, various nanomaterials have emerged as an exciting tool in cancer
theranostic applications due to their multifunctional property and intrinsic molecular property …

[HTML][HTML] Aptamer-enabled nanomaterials for therapeutics, drug targeting and imaging

M Liu, L Wang, Y Lo, SCC Shiu, AB Kinghorn… - Cells, 2022 - mdpi.com
A wide variety of nanomaterials have emerged in recent years with advantageous properties
for a plethora of therapeutic and diagnostic applications. Such applications include drug …

Advancements in redox-sensitive micelles as nanotheranostics: a new horizon in cancer management

A Sikder, G Vambhurkar, E Amulya… - Journal of Controlled …, 2022 - Elsevier
Abstract World Health Organisation (WHO) delineated cancer as one of the foremost
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …

[HTML][HTML] Application of photoactive compounds in cancer theranostics: review on recent trends from photoactive chemistry to artificial intelligence

P Szymaszek, M Tyszka-Czochara, J Ortyl - Molecules, 2024 - mdpi.com
According to the World Health Organization (WHO) and the International Agency for
Research on Cancer (IARC), the number of cancer cases and deaths worldwide is predicted …

Systematic review of cancer targeting by nanoparticles revealed a global association between accumulation in tumors and spleen

AS Drozdov, PI Nikitin, JM Rozenberg - International journal of molecular …, 2021 - mdpi.com
Active targeting of nanoparticles toward tumors is one of the most rapidly developing topics
in nanomedicine. Typically, this strategy involves the addition of cancer-targeting …

[HTML][HTML] Lipid-based nanocarriers: Bridging diagnosis and cancer therapy

A Giordano, AC Provenza, G Reverchon, L Baldino… - Pharmaceutics, 2024 - mdpi.com
Theranostics is a growing field that matches diagnostics and therapeutics. In this approach,
drugs and techniques are uniquely coupled to diagnose and treat medical conditions …

Research advances in integrated theranostic probes for tumor fluorescence visualization and treatment

J Xing, Q Gong, OU Akakuru, C Liu, R Zou, A Wu - Nanoscale, 2020 - pubs.rsc.org
At present, cancer is obviously a major threat to human health worldwide. Accurate
diagnosis and treatment are in great demand and have become an effective method to …