2021 European Heart Rhythm Association practical guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation

J Steffel, R Collins, M Antz, P Cornu, L Desteghe… - Ep …, 2021 - academic.oup.com
1Department of Cardiology, Division of Electrophysiology, University Heart Center Zurich,
Switzerland; 2Age-Related Health Care, Tallaght University Hospital/Department of …

2021 update of the International Council for Standardization in Haematology recommendations for laboratory measurement of direct oral anticoagulants

J Douxfils, DM Adcock, SM Bates… - Thrombosis and …, 2021 - thieme-connect.com
In 2018, the International Council for Standardization in Haematology (ICSH) published a
consensus document providing guidance for laboratories on measuring direct oral …

International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of direct oral anticoagulants

RC Gosselin, DM Adcock, SM Bates… - Thrombosis and …, 2018 - thieme-connect.com
This guidance document was prepared on behalf of the International Council for
Standardization in Haematology (ICSH) for providing haemostasis-related guidance …

Pharmacogenetics of bleeding and thromboembolic events in direct oral anticoagulant users

J Lähteenmäki, AL Vuorinen, J Pajula… - Clinical …, 2021 - Wiley Online Library
This study aimed to analyze associations between genetic variants and the occurrence of
clinical outcomes in dabigatran, apixaban, and rivaroxaban users. This was a retrospective …

[HTML][HTML] Antithrombotic treatment in patients with hemophilia: an EHA-ISTH-EAHAD-ESO clinical practice guidance

REG Schutgens, V Jimenez-Yuste, M Escobar… - …, 2023 - journals.lww.com
Cardiovascular disease is an emerging medical issue in patients with hemophilia (PWH)
and its prevalence is increasing up to 15% in PWH in the United States. Atrial fibrillation …

[HTML][HTML] Fixed dose rivaroxaban can be used in extremes of bodyweight: a population pharmacokinetic analysis

V Speed, B Green, LN Roberts, S Woolcombe… - Journal of Thrombosis …, 2020 - Elsevier
Background Emerging safety and efficacy data for rivaroxaban suggest traditional therapy
and rivaroxaban are comparable in the morbidly obese. However, real‐world data that …

Drug interactions and pharmacogenetic factors contribute to variation in apixaban concentration in atrial fibrillation patients in routine care

M Gulilat, D Keller, B Linton, AD Pananos… - Journal of Thrombosis …, 2020 - Springer
Factor Xa-inhibitor apixaban is an oral anticoagulant prescribed in atrial fibrillation (AF) for
stroke prevention. Its pharmacokinetic profile is known to be affected by cytochrome P450 …

[HTML][HTML] Monitoring of anticoagulation in thrombotic antiphospholipid syndrome

H Cohen, M Efthymiou, KMJ Devreese - Journal of Thrombosis and …, 2021 - Elsevier
Anticoagulation is central to the management of thrombotic antiphospholipid syndrome
(APS). The standard anticoagulant treatment for thrombotic APS is life‐long warfarin or an …

Snake venoms in diagnostic hemostasis and thrombosis

GW Moore - Seminars in thrombosis and hemostasis, 2022 - thieme-connect.com
Snake venoms have evolved primarily to immobilize and kill prey, and consequently, they
contain some of the most potent natural toxins. Part of that armory is a range of hemotoxic …

Apixaban concentration variability and relation to clinical outcomes in real-life patients with atrial fibrillation

A Mavri, N Vene, M Božič-Mijovski, M Miklič… - Scientific Reports, 2021 - nature.com
In some clinical situations, measurements of anticoagulant effect of apixaban may be
needed. We investigated the inter-and intra-individual apixaban variability in patients with …