Crosstalk between N6-methyladenosine modification and circular RNAs: current understanding and future directions

X Wang, R Ma, X Zhang, L Cui, Y Ding, W Shi, C Guo… - Molecular cancer, 2021 - Springer
Abstract N 6-methyladenosine (m 6 A) is a prevalent internal modification in eukaryotic
RNAs regulated by the so-called “writers”,“erasers”, and “readers”. m 6 A has been …

Exosomal RNAs: novel potential biomarkers for diseases—a review

J Wang, BL Yue, YZ Huang, XY Lan, WJ Liu… - International Journal of …, 2022 - mdpi.com
Exosomes are a subset of nano-sized extracellular vesicles originating from endosomes.
Exosomes mediate cell-to-cell communication with their cargos, which includes mRNAs …

Exploring the multifaceted biologically relevant roles of circRNAs: from regulation, translation to biomarkers

P Hoque, B Romero, RE Akins, M Batish - Cells, 2023 - mdpi.com
CircRNAs are a category of regulatory RNAs that have garnered significant attention in the
field of regulatory RNA research due to their structural stability and tissue-specific …

[HTML][HTML] Circular RNAs modulate Hippo-YAP signaling: functional mechanisms in cancer

J Qadir, F Li, BB Yang - Theranostics, 2022 - ncbi.nlm.nih.gov
The Hippo signaling pathway is an evolutionarily conserved network that regulates organ
size and tissue homeostasis in mammals. This pathway controls various cell functions, such …

Circular RNA circSMAD4 regulates cardiac fibrosis by targeting miR-671-5p and FGFR2 in cardiac fibroblasts

A Jeong, Y Lim, T Kook, DH Kwon, YK Cho… - … Therapy-Nucleic Acids, 2023 - cell.com
Heart failure is a leading cause of death and is often accompanied by activation of quiescent
cardiac myofibroblasts, which results in cardiac fibrosis. In this study, we aimed to identify …

Interactions between circRNA and protein in breast cancer

B Yang, YW Wang, K Zhang - Gene, 2023 - Elsevier
Circular RNA (circRNA) is a newly discovered endogenous non-coding RNA that plays
important roles in the occurrence and development of various cancers. Current research …

Circular intronic RNA circTTN inhibits host gene transcription and myogenesis by recruiting PURB proteins to form heterotypic complexes

N Ai, Z Yu, X Xu, S Liufu, K Wang, S Huang… - International Journal of …, 2023 - mdpi.com
Muscle cell growth plays an important role in skeletal muscle development. Circular RNAs
(circRNAs) have been proven to be involved in the regulation of skeletal muscle growth and …

Circular RNA PIP5K1A act as microRNA-552-3p sponge to regulates inflammation, oxidative damage in glucolipotoxicity-induced pancreatic INS-1 β-cells via Janus …

L Ren - Bioengineered, 2022 - Taylor & Francis
Elevated level of glucolipotoxicity induces the loss of pancreatic β-cells functions and plays
an important role in the development of type 2 diabetes (T2DM). Previous studies have …

CircTCF4 suppresses proliferation and differentiation of goat skeletal muscle satellite cells independent from AGO2 binding

S Zheng, L Li, H Zhou, X Zhang, X Xu, D Dai… - International Journal of …, 2022 - mdpi.com
The proliferation and differentiation of mammalian skeletal muscle satellite cells (MuSCs)
are highly complicated. Apart from the regulatory signaling cascade driven by the protein …

circUBE3C modulates myoblast development by binding to miR‐191 and upregulating the expression of p27

H Yang, B Yue, S Yang, A Qi, Y Yang… - Journal of Cellular …, 2024 - Wiley Online Library
Abstract Noncoding RNAs, including miRNAs (microRNAs) and circRNAs (circular RNA),
are crucial regulators of myoblast proliferation and differentiation during muscle …