HIV-1 protease inhibitors continue to play an important role in the treatment of HIV/AIDS,
transforming this deadly ailment into a more manageable chronic infection. Over the years …

Carbon–carbon cross‐coupling reactions are among the most important processes in
organic chemistry, and Suzuki–Miyaura reactions are among the most widely used protocols …

Microwave technology has become very important in synthesis and it is reasonable to assert
that there are now very few areas of synthetic organic chemistry that have not been shown to …

The rhodium (I)-catalyzed reaction of alkynes with 2-bromophenylboronic acids in the
presence of paraformaldehyde resulted in a CO gas-free carbonylative cyclization, yielding …

A significant number of antiviral agents used in clinical practice are amino acids, short
peptides, or peptidomimetics. Among them, several HIV protease inhibitors (eg lopinavir …

Mycobacterium tuberculosis glutamine synthetase (Mt GS) is a promising target for
antituberculosis drug discovery. In a recent high-throughput screening study we identified …

A selective overview of the recent developments of microwave‐assisted, transition‐metal‐
catalysed C–C and C–N bond‐forming reactions is presented. Microwave‐assisted …

Cinnamaldehyde derivatives were synthesized in good to excellent yields in one step by a
mild and selective, base-free palladium (II)-catalyzed oxidative Heck reaction starting from …

A facile and efficient methodology for direct synthesis of 5-aryl-2′-deoxyuridines was
developed through ligand-free Suzuki–Miyaura cross-coupling reactions starting from totally …

The unique properties of microwave in situ heating offer unparalleled opportunities for
medicinal chemists to speed up lead optimisation processes in early drug discovery. The …