Nanoparticles for topical drug delivery: Potential for skin cancer treatment
V Krishnan, S Mitragotri - Advanced Drug Delivery Reviews, 2020 - Elsevier
Nanoparticles offer new opportunities for the treatment of skin diseases. The barrier function
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …
Natural product-loaded lipid-based nanocarriers for skin cancer treatment: An overview
The skin is essential for body protection and regulating physiological processes. It is the
largest organ and serves as the first-line barrier against UV radiation, harmful substances …
largest organ and serves as the first-line barrier against UV radiation, harmful substances …
[HTML][HTML] Topical delivery of nanoemulsions for skin cancer treatment
Skin cancer chemotherapeutics often lead to the development of severe cytotoxicity,
compelling the development of novel delivery systems to not only enhance therapeutic …
compelling the development of novel delivery systems to not only enhance therapeutic …
Fractional laser-assisted topical delivery leads to enhanced, accelerated and deeper cutaneous 5-fluorouracil uptake
ABSTRACT Background: Topical 5-Fluorouracil (5-FU) exhibits suboptimal efficacy for non-
melanoma skin cancer, attributed to insufficient intracutaneous penetration. This study …
melanoma skin cancer, attributed to insufficient intracutaneous penetration. This study …
Localized topical drug delivery systems for skin cancer: Current approaches and future prospects
Topical drug delivery presents a novel substitute to the conventional drug-distribution routes
of oral delivery and injection. Apart from the simplicity and non-invasiveness, the skin also …
of oral delivery and injection. Apart from the simplicity and non-invasiveness, the skin also …
Topical Micro-Emulsion of 5-Fluorouracil by a Twin Screw Processor-Based Novel Continuous Manufacturing Process for the Treatment of Skin Cancer: Preparation …
AN Nikam, A Jacob, R Raychaudhuri, G Fernandes… - Pharmaceutics, 2023 - mdpi.com
5-Fluorouracil (5-FU), a BCS class III drug, has low oral bioavailability and is cytotoxic in
nature causing severe systemic side effects when administered through the intravenous …
nature causing severe systemic side effects when administered through the intravenous …
Topically applied lipid-and surfactant-based nanoparticles in the treatment of skin disorders
E Desmet, M Van Gele, J Lambert - Expert opinion on drug delivery, 2017 - Taylor & Francis
Introduction: In the treatment of dermatological disorders, topical drug administration is a
mainstay. However, nanoparticle-based carrier systems could improve and expand the …
mainstay. However, nanoparticle-based carrier systems could improve and expand the …
Recent advances in lipid nanocarriers applicable in the fight against cancer
J Jampílek, K Kráľová - Nanoarchitectonics in biomedicine, 2019 - Elsevier
Cancer is a class of diseases characterized by out-of-control cell growth (tumors); over 100
different types of cancer are known and classified by the type of cell that is initially affected …
different types of cancer are known and classified by the type of cell that is initially affected …
Insights from a Box–Behnken optimization study of microemulsions with salicylic acid for acne therapy
The present study brings to attention a method to develop salicylic acid-based oil in water
(O/W) microemulsions using a tensioactive system based on Tween 80, lecithin, and …
(O/W) microemulsions using a tensioactive system based on Tween 80, lecithin, and …
Study of 5-fluorouracil loaded chitosan nanoparticles for treatment of skin cancer
Background: The purpose of this study was to formulate, characterize and in-vitro cytotoxicity
of 5-Fluorouracil loaded controlled release nanoparticles for the treatment of skin cancer …
of 5-Fluorouracil loaded controlled release nanoparticles for the treatment of skin cancer …