Dendritic spines are small, thin, specialized protrusions from neuronal dendrites, primarily
localized in the excitatory synapses. Sophisticated imaging techniques revealed that …

Schizophrenia, autism and intellectual disabilities are best understood as spectrums of
diseases that have broad sets of causes. However, it is becoming evident that these …

Schizophrenia (SZ) is a mental disorder whereby due to the secretion of specific chemicals
in the brain, the function of some brain regions is out of balance, leading to the lack of …

Schizophrenia is currently classified as a psychotic disorder. This article posits that this
emphasis on psychosis is a conceptual fallacy that has greatly contributed to the lack of …

Schizophrenia is a neurodevelopmental disorder whose clinical features include
impairments in perception, cognition and motivation. These impairments reflect alterations in …

Cognitive impairment is a core symptom domain of schizophrenia. The effect of
antipsychotics, the cornerstone of treatment in schizophrenia, on this domain is not fully …

While the hippocampal formation and the prefrontal cortex each have a well-established role
in cognitive and mnemonic processes, the extent and manner in which these structures …

Impairments in certain cognitive functions, such as working memory, are core features of
schizophrenia. Convergent findings indicate that a deficiency in signalling through the TrkB …

The serotonergic pathways originating in the dorsal and median raphe nuclei (DR and MnR,
respectively) are critically involved in cortical function. Serotonin (5-HT), acting on …

Adherence to antipsychotics improves outcome in schizophrenia. There is a lack of
consensus on which factors most influence adherence behaviour and methodological …