Since the beginning of pharmaceutical research, drug delivery methods have been an integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …
Medicine relies on the use of pharmacologically active agents (drugs) to manage and treat disease. However, drugs are not inherently effective; the benefit of a drug is directly related …
N Majumder, NG Das, SK Das - Therapeutic delivery, 2020 - Taylor & Francis
Polymeric micelles have gained interest as novel drug delivery systems for the treatment and diagnosis of cancer, as they offer several advantages over conventional drug therapies …
J Zhao, W Cui - Advanced Fiber Materials, 2020 - Springer
Despite great efforts and advancement in the treatment of cancer, tumor recurrence and metastasis remain significant challenges and demand novel therapy strategies. Recently …
M Xu, X Han, H Xiong, Y Gao, B Xu, G Zhu, J Li - Molecules, 2023 - mdpi.com
Cancer continues to pose a severe threat to global health, making pursuing effective treatments more critical than ever. Traditional therapies, although pivotal in managing …
Polymer-based drug delivery depots have been investigated over the last several decades as a means to improve upon the lack of tumor targeting and severe systemic morbidities …
The delivery of drugs through targeted nanocarriers that are internalized by cells provides an alternative route to diffusion of drugs into cells. Growth factor or vitamin interactions with …
R Duncan - Nature reviews cancer, 2006 - nature.com
The transfer of polymer–protein conjugates into routine clinical use, and the clinical development of polymer–anticancer-drug conjugates, both as single agents and as …
Chemotherapeutic drugs have multiple drawbacks, including severe side effects and suboptimal therapeutic efficacy. Nanomedicines assist in improving the biodistribution and …