Isatin based 1, 2, 3-triazole derivatives as antimicrobial agents: Synthesis, in silico docking and molecular dynamics simulations
With the aim to identify new antimicrobials, in the present study a new series of isatin based
1, 2, 3-triazoles (5a-5f & 6a-6f) has been synthesized through CuAAC click reaction and …
1, 2, 3-triazoles (5a-5f & 6a-6f) has been synthesized through CuAAC click reaction and …
Molecular Docking and Molecular Dynamics Simulations of Synthesized Thiazole‐Isatin‐1, 2, 3‐triazole Hybrids as Promising Inhibitors for DNA Gyrase and Sterol …
In the present work, a new class of thiazole‐isatin‐1, 2, 3‐triazole hybrids (5 a–5 p) and
precursor alkyne hybrids (6 a–6 d) has been reported with their in‐silico studies. After …
precursor alkyne hybrids (6 a–6 d) has been reported with their in‐silico studies. After …
Novel hybrid motifs of 2-(2-pyridinyl)-1H-benzo [d] imidazole-1, 2, 3-triazole: Synthesis, anticancer assessment, and in silico study
SD Al-Qahtani, GM Al-Senani - Journal of Molecular Structure, 2024 - Elsevier
Abstract A new category of 1, 2, 3-triazole-pyridine-benzo [d] imidazole hybrids (12–21)
were prepared by a Cu (I)-catalyzed Alkyne-Azide Cyclic-addition (CuAAC) procedure …
were prepared by a Cu (I)-catalyzed Alkyne-Azide Cyclic-addition (CuAAC) procedure …
Pyrazoline Spiro-oxindole tethered 1, 2, 3-triazole hybrids: Design, synthesis, antimicrobial efficacy and molecular modelling studies
Inspired from the important applications of spirocyclic compounds in medicinal chemistry, a
new series of pyrazoline Spiro-oxindole tethered 1, 2, 3-triazole hybrids was reported via Cu …
new series of pyrazoline Spiro-oxindole tethered 1, 2, 3-triazole hybrids was reported via Cu …
Synthesis, Characterization, Antimicrobial and In Silico Studies of isatin Schiff base linked 1, 2, 3‐triazole hybrids
A new series of isatin‐Schiff base linked 1, 2, 3‐triazole hybrids has been synthesized using
CuAAC approach from (E)‐3‐(phenylimino)‐1‐(prop‐2‐yn‐1‐yl) indolin‐2‐one derivatives …
CuAAC approach from (E)‐3‐(phenylimino)‐1‐(prop‐2‐yn‐1‐yl) indolin‐2‐one derivatives …
Two step one‐pot synthesis of 7‐azaindole linked 1, 2, 3‐triazole hybrids: In‐vitro and in‐silico antimicrobial evaluation
Herein, we report design, synthesis and characterization of a new library of 7‐azaindole N‐
ethyl linked 1, 2, 3‐triazoles containing ethylene as a spacer unit, and evaluation of all the …
ethyl linked 1, 2, 3‐triazoles containing ethylene as a spacer unit, and evaluation of all the …