Inflammatory cytokines in the pathogenesis of cardiovascular disease and cancer

MN Amin, SA Siddiqui, M Ibrahim… - SAGE open …, 2020 - journals.sagepub.com
Inflammatory cytokines are highly inducible small glycoproteins or regulatory proteins of low
molecular weight secreted by different cell types. They regulate intercellular communication …

Ovarian cancer: etiology, risk factors, and epidemiology

J Hunn, GC Rodriguez - Clinical obstetrics and gynecology, 2012 - journals.lww.com
Little is known regarding the early aspects of ovarian carcinogenesis. As a consequence,
the identification of women at risk for the disease is based primarily on clinical grounds, with …

Chronic inflammation towards cancer incidence: A systematic review and meta-analysis of epidemiological studies

N Michels, C van Aart, J Morisse, A Mullee… - Critical Reviews in …, 2021 - Elsevier
This systematic review and meta-analysis provides epidemiological data on the relationship
between chronic inflammation, as measured by inflammatory blood parameters, and cancer …

The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer

SS Savant, S Sriramkumar, HM O'Hagan - Cancers, 2018 - mdpi.com
Inflammation plays a role in the initiation and development of many types of cancers,
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …

Inflammation and ovarian cancer

A Macciò, C Madeddu - Cytokine, 2012 - Elsevier
Epithelial ovarian cancer (EOC) is a highly lethal gynecological cancer for which overall
prognosis has remained poor over the past few decades. A number of theories have been …

Role of inflammation in benign gynecologic disorders: from pathogenesis to novel therapies

A AlAshqar, L Reschke, GW Kirschen… - Biology of …, 2021 - academic.oup.com
Emerging evidence supports the notion that inflammation fosters the development of
common benign gynecologic disorders, including uterine leiomyoma, endometriosis, and …

Endometriosis-associated ovarian cancer: a review of pathogenesis

MJ Worley Jr, WR Welch, RS Berkowitz… - International journal of …, 2013 - mdpi.com
Endometriosis is classically defined as the presence of endometrial glands and stroma
outside of the endometrial lining and uterine musculature. With an estimated frequency of …

Circulating adipokines and risk of obesity related cancers: A systematic review and meta-analysis

YS Yoon, AR Kwon, YK Lee, SW Oh - Obesity research & clinical practice, 2019 - Elsevier
Background Obesity can influence on carcinogenesis through alterations in adipokines and
subsequent inflammatory changes. This meta-analysis was aimed to comprehensively …

The role of cathelicidin LL-37 in cancer development

E Piktel, K Niemirowicz, U Wnorowska, M Wątek… - Archivum immunologiae …, 2016 - Springer
LL-37 is a C-terminal peptide proteolytically released from 18 kDa human cathelicidin
protein (hCAP18). Chronic infections, inflammation, tissue injury and tissue regeneration are …

Immunotherapeutic interleukin-6 or interleukin-6 receptor blockade in cancer: challenges and opportunities

NC Kampan, SD Xiang, OM McNally… - Current medicinal …, 2018 - ingentaconnect.com
Interleukin 6 (IL-6), a well-known pro-inflammatory cytokine with pleiotropic activity is a
central player in chronic inflammatory diseases including cancers. Therefore, blockade of …