Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural Product …, 2016 - pubs.rsc.org
Covering: 2014. Previous review: Nat. Prod. Rep., 2015, 32, 116–211 This review covers the
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …

Ancient venom systems: a review on cnidaria toxins

M Jouiaei, AA Yanagihara, B Madio, TJ Nevalainen… - Toxins, 2015 - mdpi.com
Cnidarians are the oldest extant lineage of venomous animals. Despite their simple
anatomy, they are capable of subduing or repelling prey and predator species that are far …

International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

S Kellenberger, L Schild - Pharmacological reviews, 2015 - ASPET
The epithelial Na+ channel (ENaC) and the acid-sensing ion channels (ASICs) form
subfamilies within the ENaC/degenerin family of Na+ channels. ENaC mediates …

Marine pharmacology in 2014–2015: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, antiviral, and …

AMS Mayer, AJ Guerrero, AD Rodríguez… - Marine Drugs, 2019 - mdpi.com
The systematic review of the marine pharmacology literature from 2014 to 2015 was
completed in a manner consistent with the 1998–2013 reviews of this series. Research in …

[PDF][PDF] Natural product reports

JW Blunt, BR Copp, RA Keyzers, MH Munroa… - Nat Prod Rep, 2016 - academia.edu
This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

A review of toxins from Cnidaria

I D'Ambra, C Lauritano - Marine drugs, 2020 - mdpi.com
Cnidarians have been known since ancient times for the painful stings they induce to
humans. The effects of the stings range from skin irritation to cardiotoxicity and can result in …

Pharmacology of acid-sensing ion channels–Physiological and therapeutical perspectives

A Baron, E Lingueglia - Neuropharmacology, 2015 - Elsevier
Abstract Development of the pharmacology of Acid-Sensing Ion Channels (ASICs) has
become a key challenge to study their structure, their molecular and cellular functions and …

Sea anemone toxins: A structural overview

B Madio, GF King, EAB Undheim - Marine drugs, 2019 - mdpi.com
Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different
molecular scaffolds reported to date. These venom components have traditionally been …

The cystine knot is responsible for the exceptional stability of the insecticidal spider toxin ω-Hexatoxin-Hv1a

V Herzig, GF King - Toxins, 2015 - mdpi.com
The inhibitor cystine knot (ICK) is an unusual three-disulfide architecture in which one of the
disulfide bonds bisects a loop formed by the two other disulfide bridges and the intervening …

Acid-sensing ion channel 3: An analgesic target

JS Dulai, ESJ Smith, T Rahman - Channels, 2021 - Taylor & Francis
Acid-sensing ion channel 3 (ASIC3) belongs to the epithelial sodium channel/degenerin
(ENaC/DEG) superfamily. There are 7 different ASIC subunits encoded by 5 different genes …