Human cytomegalovirus latency and reactivation in allogeneic hematopoietic stem cell transplant recipients

L Stern, B Withers, S Avdic, D Gottlieb… - Frontiers in …, 2019 - frontiersin.org
Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …

[HTML][HTML] Herpes virus reactivation in astronauts during spaceflight and its application on earth

BV Rooney, BE Crucian, DL Pierson… - Frontiers in …, 2019 - frontiersin.org
Latent herpes virus reactivation has been demonstrated in astronauts during shuttle (10–16
days) and International Space Station (≥ 180 days) flights. Following reactivation, viruses …

HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions

CS Nelson, T Huffman, JA Jenks… - Proceedings of the …, 2018 - National Acad Sciences
Human cytomegalovirus (HCMV) is the most common congenital infection worldwide,
frequently causing hearing loss and brain damage in afflicted infants. A vaccine to prevent …

Dual inhibition of innate immunity and apoptosis by human cytomegalovirus protein UL37x1 enables efficient virus replication

Y Ren, A Wang, D Wu, C Wang, M Huang, X Xiong… - Nature …, 2022 - nature.com
Immune evasion and inhibition of apoptosis are required for successful virus infection.
However, inhibition of apoptosis can increase antiviral immune responses, which can then …

[HTML][HTML] The CD4+ T cell response to human cytomegalovirus in healthy and immunocompromised people

EY Lim, SE Jackson, MR Wills - Frontiers in cellular and infection …, 2020 - frontiersin.org
While CD8+ T cells specific for human cytomegalovirus (HCMV) have been extensively
studied in both healthy HCMV seropositive carriers and patients undergoing …

[HTML][HTML] Advances in the treatment of cytomegalovirus

BA Krishna, MR Wills, JH Sinclair - British Medical Bulletin, 2019 - ncbi.nlm.nih.gov
Advances in the treatment of cytomegalovirus - PMC Back to Top Skip to main content NIH
NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation …

Diversity of tissue-resident NK cells

H Peng, Z Tian - Seminars in immunology, 2017 - Elsevier
Although natural killer (NK) cells were initially named for their spontaneous tumor-killing
capacity, their concept has been greatly expanded with more than 40 years of extensive …

A practical review of cytomegalovirus in gastroenterology and hepatology

AY Fakhreddine, CT Frenette… - … research and practice, 2019 - Wiley Online Library
Human cytomegalovirus (CMV) is a ubiquitous Herpesviridae virus with a wide spectrum of
pathology in humans. Host immunity is a major determinant of the clinical manifestation of …

Latent cytomegalovirus (CMV) infection does not detrimentally alter T cell responses in the healthy old, but increased latent CMV carriage is related to expanded CMV …

SE Jackson, GX Sedikides, G Okecha… - Frontiers in …, 2017 - frontiersin.org
Human cytomegalovirus (HCMV) primary infection and periodic reactivation of latent virus is
generally well controlled by T-cell responses in healthy people. In older donors, overt HCMV …

Sleepless latency of human cytomegalovirus

E Poole, J Sinclair - Medical microbiology and immunology, 2015 - Springer
As with all human herpesviruses, human cytomegalovirus (HCMV) persists for the lifetime of
the host by establishing a latent infection, which is broken by periodic reactivation events …