Functionalized silk fibroin nanofibers as drug carriers: Advantages and challenges

M Farokhi, F Mottaghitalab, RL Reis… - Journal of Controlled …, 2020 - Elsevier
Electrospinning is well thought of as the most potent nanofiber producing technique, which
is applicable in biomedical fields. The generation of electrospun nanofibers as drug carriers …

Biomaterials against bone infection

M Vallet‐Regí, D Lozano, B González… - Advanced …, 2020 - Wiley Online Library
Chronic bone infection is considered as one of the most problematic biofilm‐related
infections. Its recurrent and resistant nature, high morbidity, prolonged hospitalization, and …

Fibroin nanoparticles: A promising drug delivery system

DT Pham, W Tiyaboonchai - Drug delivery, 2020 - Taylor & Francis
Fibroin is a dominant silk protein that possesses ideal properties as a biomaterial for drug
delivery. Recently, the development of fibroin nanoparticles (FNPs) for various biomedical …

[HTML][HTML] Dual-functional composite scaffolds for inhibiting infection and promoting bone regeneration

Y Cui, H Liu, Y Tian, Y Fan, S Li, G Wang, Y Wang… - Materials Today Bio, 2022 - Elsevier
The treatment of infected bone defects is an intractable problem in orthopedics. It comprises
two critical parts, namely that of infection control and bone defect repair. According to these …

Turning toxic nanomaterials into a safe and bioactive nanocarrier for co-delivery of DOX/pCRISPR

N Rabiee, M Bagherzadeh, AM Ghadiri… - ACS Applied Bio …, 2021 - ACS Publications
Hybrid bioactive inorganic–organic carbon-based nanocomposites of reduced graphene
oxide (rGO) nanosheets enlarged with multi-walled carbon nanotubes (MWCNTs) were …

Dual drug delivery system based on pH-sensitive silk fibroin/alginate nanoparticles entrapped in PNIPAM hydrogel for treating severe infected burn wound

F Rezaei, S Damoogh, RL Reis, SC Kundu… - …, 2020 - iopscience.iop.org
Herein, the pH-sensitive vancomycin (VANCO) loaded silk fibroin-sodium alginate
nanoparticles (NPs) embedded in poly (N-isopropylacrylamide)(PNIPAM) hydrogel …

Crosslinked-polyvinyl alcohol-carboxymethyl cellulose/ZnO nanocomposite fibrous mats containing erythromycin (PVA-CMC/ZnO-EM): Fabrication, characterization …

B Darbasizadeh, Y Fatahi, B Feyzi-Barnaji… - International journal of …, 2019 - Elsevier
Recently, nanocomposite nanofibers have been extensively used for biomedical
applications. It is expected that simultaneous incorporation of antibiotic drugs and ZnO …

Dual drug delivery system of teicoplanin and phenamil based on pH-sensitive silk fibroin/sodium alginate hydrogel scaffold for treating chronic bone infection

H Motasadizadeh, M Tavakoli, S Damoogh… - Biomaterials …, 2022 - Elsevier
For effective treatment of infected bone, it is essential to use local drug delivery systems with
the ability to deliver both antibiotics and osteoinductive factors. Herein, a pH-sensitive silk …

Synthesis and characterization of injectable thermosensitive hydrogel based on Pluronic-grafted silk fibroin copolymer containing hydroxyapatite nanoparticles as …

A Daneshvar, M Farokhi, S Bonakdar… - International Journal of …, 2024 - Elsevier
Injectable hydrogels are promising for bone tissue engineering due to their minimally
invasive application and adaptability to irregular defects. This study presents the …

Metal-organic frameworks for simultaneous gene and small molecule delivery in vitro and in vivo

A Ringaci, AV Yaremenko, KG Shevchenko… - Chemical Engineering …, 2021 - Elsevier
Nanoparticles based on metal–organic frameworks (nMOF) became one of the most
promising class of drug delivery vehicles due to their ability to transport a great range of …