There is substantial need for molecularly defined tumor antigens to prime cytotoxic T cells in
vivo for cancer immunotherapy, especially in the case of tumor entities for which only a few …

This paper provides guidance on how to assess the safety of foods derived from genetically
modified crops (GM crops); it summarises conclusions and recommendations of Working …

Background The generation of interferon-gamma (IFN-γ) by MHC class II activated CD4+ T
helper cells play a substantial contribution in the control of infections such as caused by …

The secretion of Interleukin‐4 (IL4) is the characteristic of T‐helper 2 responses. IL4 is a
cytokine produced by CD4+ T cells in response to helminthes and other extracellular …

Vaxign is the first web‐based vaccine design system that predicts vaccine targets based on
genome sequences using the strategy of reverse vaccinology. Predicted features in the …

Cytotoxic T lymphocyte (CTL) epitopes are potential candidates for subunit vaccine design
for various diseases. Most of the existing T cell epitope prediction methods are indirect …

One of the great surprises of the biologics revolution has been the discovery that
recombinant human proteins, including monoclonals of human origin, can cause immune …

Coccidioidomycosis is caused by the dimorphic fungi in the genus Coccidioides. These
fungi live as mycelia in the soil of desert areas of the American Southwest, and when the …

Vaccine informatics is an emerging research area that focuses on development and
applications of bioinformatics methods that can be used to facilitate every aspect of the …

Introduction The field of cancer therapy has undergone a major transformation in less than a
decade due to the introduction of checkpoint inhibitors, the advent of next generation …