Aging is a complex biological process characterized by hallmark features accumulating over
the life course, shaping the individual's aging trajectory and subsequent disease risks. There …

The search for reliable indicators of biological age, rather than chronological age, has been
ongoing for over three decades, and until recently, largely without success. Advances in the …

INTRODUCTION Telomeres are DNA-protein complexes located at the end of chromosomes
that protect chromosome ends from degradation and fusion. The DNA component of …

Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes.
Telomere length is a marker of DNA damage, which is often considered a biomarker for …

Telomere attrition is associated with increased morbidity and mortality of various age-related
diseases. Reports of association between telomere length (TL) and all-cause mortality …

Background Cigarette smoking is a risk factor for ageing-related disease, but its association
with biological ageing, indicated by telomere length, is unclear. Methods We systematically …

Telomeres are the heterochromatic repeat regions at the ends of eukaryotic chromosomes,
whose length is considered to be a determinant of biological ageing. Normal ageing itself is …

Sexual dimorphism is a key factor to consider in the ageing process given the impact that it
has on life expectancy. The oxidative-inflammatory theory of ageing states that the ageing …

Telomere length (TL) has become a biomarker of increasing interest within ecology and
evolutionary biology, and has been found to predict subsequent survival in some recent …

Importance Psychological stress contributes to numerous diseases and may do so in part
through damage to telomeres, protective non-coding segments on the ends of …