LAMP-on-a-chip: Revising microfluidic platforms for loop-mediated DNA amplification

H Zhang, Y Xu, Z Fohlerova, H Chang, C Iliescu… - TrAC Trends in …, 2019 - Elsevier
Nucleic acid amplification for the detection of infectious diseases, food pathogens, or
assessment of genetic disorders require a laboratory setting with specialized equipment and …

Microfluidic designs and techniques using lab-on-a-chip devices for pathogen detection for point-of-care diagnostics

AM Foudeh, TF Didar, T Veres, M Tabrizian - Lab on a Chip, 2012 - pubs.rsc.org
Effective pathogen detection is an essential prerequisite for the prevention and treatment of
infectious diseases. Despite recent advances in biosensors, infectious diseases remain a …

Brief review of monitoring methods for loop-mediated isothermal amplification (LAMP)

X Zhang, SB Lowe, JJ Gooding - Biosensors and Bioelectronics, 2014 - Elsevier
The loop-mediated isothermal amplification (LAMP) technique has the potential to
revolutionize molecular biology because it allows DNA amplification under isothermal …

A glucose meter interface for point-of-care gene circuit-based diagnostics

E Amalfitano, M Karlikow, M Norouzi, K Jaenes… - Nature …, 2021 - nature.com
Recent advances in cell-free synthetic biology have given rise to gene circuit-based sensors
with the potential to provide decentralized and low-cost molecular diagnostics. However, it …

Impact of primer dimers and self-amplifying hairpins on reverse transcription loop-mediated isothermal amplification detection of viral RNA

RJ Meagher, A Priye, YK Light, C Huang, E Wang - Analyst, 2018 - pubs.rsc.org
Loop-mediated isothermal amplification (LAMP), coupled with reverse transcription (RT),
has become a popular technique for detection of viral RNA due to several desirable …

Emerging loop-mediated isothermal amplification-based microchip and microdevice technologies for nucleic acid detection

M Safavieh, MK Kanakasabapathy… - ACS biomaterials …, 2016 - ACS Publications
Rapid, sensitive, and selective pathogen detection is of paramount importance in infectious
disease diagnosis and treatment monitoring. Currently available diagnostic assays based …

Classification of multiple DNA dyes based on inhibition effects on real-time loop-mediated isothermal amplification (LAMP): prospect for point of care setting

TL Quyen, TA Ngo, DD Bang, M Madsen… - Frontiers in …, 2019 - frontiersin.org
LAMP has received great interest and is widely utilized in life sciences for nucleic acid
analysis. To monitor a real-time LAMP assay, a fluorescence DNA dye is an indispensable …

Principles and applications of loop-mediated isothermal amplification to point-of-care tests

JW Park - Biosensors, 2022 - mdpi.com
For the identification of nucleic acids, which are important biomarkers of pathogen-mediated
diseases and viruses, the gold standard for NA-based diagnostic applications is polymerase …

Gene-Z: a device for point of care genetic testing using a smartphone

RD Stedtfeld, DM Tourlousse, G Seyrig, TM Stedtfeld… - Lab on a Chip, 2012 - pubs.rsc.org
By 2012, point of care (POC) testing will constitute roughly one third of the $59 billion in vitro
diagnostics market. The ability to carry out multiplexed genetic testing and wireless …

Loop-Mediated Isothermal Amplification for Salmonella Detection in Food and Feed: Current Applications and Future Directions

Q Yang, KJ Domesle, B Ge - Foodborne pathogens and disease, 2018 - liebertpub.com
Loop-mediated isothermal amplification (LAMP) has become a powerful alternative to
polymerase chain reaction (PCR) for pathogen detection in clinical specimens and food …