Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis

S Zhu, W Chen, A Masson, YP Li - Cell Discovery, 2024 - nature.com
The initiation of osteogenesis primarily occurs as mesenchymal stem cells undergo
differentiation into osteoblasts. This differentiation process plays a crucial role in bone …

The critical role of toll-like receptor 4 in bone remodeling of osteoporosis: from inflammation recognition to immunity

X Zhu, L Du, L Zhang, L Ding, W Xu, X Lin - Frontiers in immunology, 2024 - frontiersin.org
Osteoporosis is a common chronic metabolic bone disorder. Recently, increasing numbers
of studies have demonstrated that Toll-like receptor 4 (TLR4, a receptor located on the …

Effects of circulating inflammatory proteins on osteoporosis and fractures: evidence from genetic correlation and Mendelian randomization study

Q Zheng, D Wang, R Lin, Z Li, Y Chen… - Frontiers in …, 2024 - frontiersin.org
Objective There is a controversy in studies of circulating inflammatory proteins (CIPs) in
association with osteoporosis (OP) and fractures, and it is unclear if these two conditions are …