Purpose Available data on the effects of anti-diabetic drugs on fracture risk are contradictory.
Therefore, our study aimed to analyze all available data on the effects of anti-diabetic drugs …

Nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic
steatohepatitis (NASH), can promote the development of cirrhosis, hepatocellular …

Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly
expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at …

Persons with type 1 or type 2 diabetes have a significantly higher fracture risk than age‐
matched persons without diabetes, attributed to disease‐specific deficits in the …

Background: Marrow adipose tissue (MAT) has been shown to be vital for regulating
metabolism and maintaining skeletal homeostasis in the bone marrow (BM) niche. As a …

Nonalcoholic fatty liver disease (NAFLD) and osteoporosis are two highly prevalent
metabolic diseases. Increasing experimental evidence supports a pathophysiological link …

Drugs may cause bone loss by lowering sex steroid levels (eg, aromatase inhibitors in
breast cancer, GnRH agonists in prostate cancer, or depot medroxyprogestone acetate …

Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–
adrenal axis, which plays a major role in the body's immune response to stress. Mast cells …

Traumatic brain injury (TBI) is one of the leading causes of death and disability among
children and young adults in the United States. In this manuscript, we assessed the utility of …

Aim Bone fragility is increasingly recognized as a relevant complication of type 2 diabetes
(T2D) and diabetic patients with fragility fractures have higher mortality rates than non …