Cocaine produces a pattern of cardiovascular responses that are associated with apparent
myocardial ischemia, arrhythmias, and other life-threatening complications in some …

Cocaine belongs to the group of psychostimulants and together with amphetamines has
been recognized as one of the most significant examples of drug abuse. Cocaine abuse is …

Among persons living with human immunodeficiency virus (HIV) infection, liver disease
remains a major cause of morbidity and mortality. While the etiologies are varied and often …

Background The simultaneous consumption of cocaine and alcohol results in the production
of cocaethylene (CE) in the liver, a highly toxic metabolite. Prior research suggests that …

Cocaine is a widely abused drug responsible for the majority of deaths ascribed to drug
overdose. Many mechanisms have been proposed in order to explain the various cocaine …

We evaluated the overall genetic damage induced by different doses of cocaine and MDMA
(3, 4‐Methylenedioxymethamphetamine) in several organs. One hour after intraperitoneal …

Substances of abuse induce alteration in neurobehavioral symptoms, which can lead to
simultaneous exacerbation of liver injury. The biochemical changes of liver are significantly …

Cocaine abuse is known to induce different types of brain-microvascular damage and many
adverse cerebrovascular effects, including cerebral vasculitis, intracranial hemorrhage …

Cocaine abuse is known to induce many adverse cardiovascular effects, including
hypertension, atherosclerosis, and aortic dissection. A major physiological event leading to …

To evaluate whether chronic cocaine abuse will increase cardiac Fas-dependent and
mitochondria-dependent apoptotic pathways, thirty-two male Wistar rats at 3–4 months of …